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    Y71H2AM.12 Ras-related protein Rab-18 [ Caenorhabditis elegans ]

    Gene ID: 175389, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Y71H2AM.12
    Official Full Name
    Ras-related protein Rab-18
    Primary source
    WormBase:WBGene00022177
    Locus tag
    CELE_Y71H2AM.12
    See related
    AllianceGenome:WB:WBGene00022177
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable GTP binding activity; GTPase activity; and protein kinase binding activity. Predicted to be involved in several processes, including Rac protein signal transduction; cytoskeleton organization; and motor neuron axon guidance. Predicted to be active in several cellular components, including cytoplasmic vesicle; cytoskeleton; and plasma membrane. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See Y71H2AM.12 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    6
    Sequence:
    Chromosome: III; NC_003281.10 (2731340..2734091, complement)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Transmembrane protein 132 homolog Neighboring gene tRNA-Pro Neighboring gene Peptidase M20 dimerization domain-containing protein Neighboring gene Cyclin N-terminal domain-containing protein Neighboring gene Carboxylesterase type B domain-containing protein Neighboring gene L-Fucosyltransferase Neighboring gene Actin interacting protein 3-like C-terminal domain-containing protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables GTP binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables GTPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein kinase binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in Rac protein signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in actin filament organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in cell chemotaxis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in cell projection assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in cortical cytoskeleton organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in establishment or maintenance of cell polarity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in motor neuron axon guidance IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of actin cytoskeleton organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of cell shape IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cell projection IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytoplasmic vesicle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytoskeleton IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Ras-related protein Rab-18
    NP_497608.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      2731340..2734091 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_065207.9 → NP_497608.1  Ras-related protein Rab-18 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_497608.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9BL44
      Conserved Domains (2) summary
      cd00154
      Location:13 → 163
      Rab; Ras-related in brain (Rab) family of small guanosine triphosphatases (GTPases)
      pfam00071
      Location:13 → 163
      Ras; Ras family
    Nucleotide Protein
    Heading Accession and Version

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