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    • Showing Current items.

    puf-7 Pumilio domain-containing protein 7 [ Caenorhabditis elegans ]

    Gene ID: 177332, updated on 9-Dec-2024

    Summary

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    Official Symbol
    puf-7
    Official Full Name
    Pumilio domain-containing protein 7
    Primary source
    WormBase:WBGene00004243
    Locus tag
    CELE_B0273.2
    See related
    AllianceGenome:WB:WBGene00004243
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable mRNA 3'-UTR binding activity. Involved in germ cell development. Predicted to be active in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See puf-7 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    4
    Sequence:
    Chromosome: IV; NC_003282.8 (5486713..5490322)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene IMV membrane protein Neighboring gene snRNA-activating protein complex subunit 3 Neighboring gene Chitotriosidase-1 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The RNA-binding proteins PUF-5, PUF-6, and PUF-7 reveal multiple systems for maternal mRNA regulation during C. elegans oogenesis. Lublin AL, et al. Dev Biol, 2007 Mar 15. PMID 17234175
    2. Characteristics and evolution of the PUF gene family in Bombyx mori and 27 other species. Zhang CD, et al. Mol Biol Rep, 2012 Jan. PMID 21598114
    3. A Caenorhabditis elegans PUF protein family with distinct RNA binding specificity. Stumpf CR, et al. RNA, 2008 Aug. PMID 18579869, Free PMC Article
    4. nos-1 and nos-2, two genes related to Drosophila nanos, regulate primordial germ cell development and survival in Caenorhabditis elegans. Subramaniam K, et al. Development, 1999 Nov. PMID 10518502
    5. The Caenorhabditis elegans pumilio homolog, puf-9, is required for the 3'UTR-mediated repression of the let-7 microRNA target gene, hbl-1. Nolde MJ, et al. Dev Biol, 2007 May 15. PMID 17412319, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables RNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables mRNA 3'-UTR binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in cell cycle IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in cell division IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in germ cell development IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in oogenesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in post-transcriptional regulation of gene expression IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Pumilio domain-containing protein 7
    NP_500820.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      5486713..5490322
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_068419.7 → NP_500820.1  Pumilio domain-containing protein 7 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_500820.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O44169
      Conserved Domains (1) summary
      cl21719
      Location:82 → 449
      Pumilio; Pumilio-family RNA binding domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O44169.1

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