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    ugt-60 Putative UDP-glucuronosyltransferase ugt-60 [ Caenorhabditis elegans ]

    Gene ID: 176366, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ugt-60
    Official Full Name
    Putative UDP-glucuronosyltransferase ugt-60
    Primary source
    WormBase:WBGene00007402
    Locus tag
    CELE_C07A9.6
    See related
    AllianceGenome:WB:WBGene00007402
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Orthologous to human UGT2A2 (UDP glucuronosyltransferase family 2 member A2). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ugt-60 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    9
    Sequence:
    Chromosome: III; NC_003281.10 (9676320..9679051, complement)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Uncharacterized protein Neighboring gene Uncharacterized protein Neighboring gene USP domain-containing protein Neighboring gene putative calcium-binding protein C07A9.5

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Role of UDP-Glycosyltransferase (ugt) Genes in Detoxification and Glycosylation of 1-Hydroxyphenazine (1-HP) in Caenorhabditis elegans. Asif MZ, et al. Chem Res Toxicol, 2024 Apr 15. PMID 38488606, Free PMC Article
    2. An anchored experimental design and meta-analysis approach to address batch effects in large-scale metabolomics. Shaver AO, et al. Front Mol Biosci, 2022. PMID 36438654, Free PMC Article
    3. UDP-glycosyltransferase family in Haemonchus contortus: Phylogenetic analysis, constitutive expression, sex-differences and resistance-related differences. Matoušková P, et al. Int J Parasitol Drugs Drug Resist, 2018 Dec. PMID 30293057, Free PMC Article
    4. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables UDP-glycosyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables UDP-glycosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables glucuronosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables glycosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Putative UDP-glucuronosyltransferase ugt-60
    NP_001021158.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      9676320..9679051 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001025987.5 → NP_001021158.1  Putative UDP-glucuronosyltransferase ugt-60 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001021158.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P34317
      Conserved Domains (2) summary
      PHA03392
      Location:253 → 464
      egt; ecdysteroid UDP-glucosyltransferase; Provisional
      cl10013
      Location:17 → 161
      Glycosyltransferase_GTB_type; Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P34317.2

    Gene LinkOut

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