ubc-16 Ubiquitin-conjugating enzyme E2 W [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: ubc-16
Official Full Name: Ubiquitin-conjugating enzyme E2 W
Primary source: WormBase:WBGene00006711
Locus tag: CELE_Y54E5B.4
See related: AllianceGenome:WB:WBGene00006711
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable ubiquitin conjugating enzyme activity. Involved in protein ubiquitination. Predicted to be active in nucleus. Is expressed in germ line and oocyte. Orthologous to human UBE2W (ubiquitin conjugating enzyme E2 W). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See ubc-16 in Genome Data Viewer

Location:: chromosome: I

Exon count:: 4

Sequence:: Chromosome: I; NC_003279.8 (14822050..14823996)

Chromosome I - NC_003279.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

Y54E5B.3 (e-PCR)
- UniSTS:312878

Y54E5B.4 (e-PCR)
- UniSTS:318679

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables ligase activity	IEA Inferred from Electronic Annotation more info
enables transferase activity	IEA Inferred from Electronic Annotation more info
enables ubiquitin conjugating enzyme activity	IBA Inferred from Biological aspect of Ancestor more info
enables ubiquitin conjugating enzyme activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in proteasome-mediated ubiquitin-dependent protein catabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein modification by small protein conjugation	IEA Inferred from Electronic Annotation more info
involved_in protein polyubiquitination	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein ubiquitination	IEA Inferred from Electronic Annotation more info
involved_in protein ubiquitination	IGI Inferred from Genetic Interaction more info	PubMed

Component	Evidence Code	Pubs
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: Ubiquitin-conjugating enzyme E2 W

NP_493587.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

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Reference assembly

Genomic

NC_003279.8 Reference assembly

Range

14822050..14823996

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_061186.5 → NP_493587.1 Ubiquitin-conjugating enzyme E2 W [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_493587.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q9XWF6

Conserved Domains (1) summary

pfam00179
Location:8 → 110

UQ_con; Ubiquitin-conjugating enzyme