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    eva-1 Protein eva-1;SUEL-type lectin domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 173355, updated on 9-Dec-2024

    Summary

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    Official Symbol
    eva-1
    Official Full Name
    Protein eva-1;SUEL-type lectin domain-containing protein
    Primary source
    WormBase:WBGene00009304
    Locus tag
    CELE_F32A7.3
    See related
    AllianceGenome:WB:WBGene00009304
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable carbohydrate binding activity. Located in M band; cell junction; and striated muscle dense body. Is expressed in body wall musculature; hypodermis; pharyngeal muscle cell; and ventral nerve cord. Orthologous to human EVA1C (eva-1 homolog C). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See eva-1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    10
    Sequence:
    Chromosome: I; NC_003279.8 (14829732..14834841, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene pseudo Neighboring gene ncRNA Neighboring gene Transmembrane protein Neighboring gene Methyltransferase-like protein 17, mitochondrial

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The MADD-3 LAMMER Kinase Interacts with a p38 MAP Kinase Pathway to Regulate the Display of the EVA-1 Guidance Receptor in Caenorhabditis elegans. D'Souza SA, et al. PLoS Genet, 2016 Apr. PMID 27123983, Free PMC Article
    2. The slit receptor EVA-1 coactivates a SAX-3/Robo mediated guidance signal in C. elegans. Fujisawa K, et al. Science, 2007 Sep 28. PMID 17901337
    3. Distinct cell guidance pathways controlled by the Rac and Rho GEF domains of UNC-73/TRIO in Caenorhabditis elegans. Marcus-Gueret N, et al. Genetics, 2012 Jan. PMID 21996675, Free PMC Article
    4. EVA-1 functions as an UNC-40 Co-receptor to enhance attraction to the MADD-4 guidance cue in Caenorhabditis elegans. Chan KK, et al. PLoS Genet, 2014 Aug. PMID 25122090, Free PMC Article
    5. Systematic Functional Characterization of Human 21st Chromosome Orthologs in Caenorhabditis elegans. Nordquist SK, et al. G3 (Bethesda), 2018 Mar 2. PMID 29367452, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables carbohydrate binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in M band HDA PubMed 
    located_in cell junction HDA PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in striated muscle dense body HDA PubMed 

    General protein information

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    Preferred Names
    Protein eva-1;SUEL-type lectin domain-containing protein
    NP_001309519.1
    • Confirmed by transcript evidence
    NP_001366909.1
    • Confirmed by transcript evidence
    NP_493590.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      14829732..14834841 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001381268.1 → NP_001366909.1  Protein eva-1 [Caenorhabditis elegans]

      Status: REVIEWED

      Conserved Domains (1) summary
      pfam02140
      Location:4 → 54
      Gal_Lectin; Galactose binding lectin domain

    2. NM_061189.7 → NP_493590.2  Protein eva-1 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_493590.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P91865, Q9XU98
      Conserved Domains (1) summary
      pfam02140
      Location:63 → 159
      Gal_Lectin; Galactose binding lectin domain

    3. NM_001322695.3 → NP_001309519.1  SUEL-type lectin domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A131MCP4
      Conserved Domains (1) summary
      pfam02140
      Location:72 → 168
      Gal_Lectin; Galactose binding lectin domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9XU98.2

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