Y55F3AM.9 Ubiquitin carboxyl-terminal hydrolase [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: Y55F3AM.9
Official Full Name: Ubiquitin carboxyl-terminal hydrolase
Primary source: WormBase:WBGene00021926
Locus tag: CELE_Y55F3AM.9
See related: AllianceGenome:WB:WBGene00021926
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable K48-linked deubiquitinase activity and cysteine-type carboxypeptidase activity. Predicted to be involved in chromatin remodeling and proteolysis. Orthologous to human MINDY1 (MINDY lysine 48 deubiquitinase 1) and MINDY2 (MINDY lysine 48 deubiquitinase 2). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See Y55F3AM.9 in Genome Data Viewer

Location:: chromosome: IV

Exon count:: 8

Sequence:: Chromosome: IV; NC_003282.8 (1006083..1009734, complement)

Chromosome IV - NC_003282.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

Y55F3A_746.b (e-PCR)
- UniSTS:323750

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables K48-linked deubiquitinase activity	IBA Inferred from Biological aspect of Ancestor more info
enables K48-linked deubiquitinase activity	IEA Inferred from Electronic Annotation more info
enables K48-linked polyubiquitin modification-dependent protein binding	IEA Inferred from Electronic Annotation more info
enables cysteine-type carboxypeptidase activity	IBA Inferred from Biological aspect of Ancestor more info
enables cysteine-type deubiquitinase activity	IEA Inferred from Electronic Annotation more info
enables cysteine-type peptidase activity	IEA Inferred from Electronic Annotation more info
enables histone deubiquitinase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in chromatin remodeling	IEA Inferred from Electronic Annotation more info
involved_in proteolysis	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: Ubiquitin carboxyl-terminal hydrolase

NP_001368251.1

Confirmed by transcript evidence

NP_500023.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003282.8 Reference assembly

Range

1006083..1009734 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_067622.5 → NP_500023.1 Ubiquitin carboxyl-terminal hydrolase [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_500023.1

Status: REVIEWED

UniProtKB/TrEMBL

Q9N370

Conserved Domains (1) summary

pfam04424
Location:83 → 199

MINDY_DUB; MINDY deubiquitinase
NM_001380029.1 → NP_001368251.1 Ubiquitin carboxyl-terminal hydrolase [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/TrEMBL

U4PEI7