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    slc-30A5 Proton-coupled zinc antiporter SLC30A5 [ Caenorhabditis elegans ]

    Gene ID: 173299, updated on 9-Dec-2024

    Summary

    Official Symbol
    slc-30A5
    Official Full Name
    Proton-coupled zinc antiporter SLC30A5
    Primary source
    WormBase:WBGene00013668
    Locus tag
    CELE_Y105E8A.3
    See related
    AllianceGenome:WB:WBGene00013668
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable zinc ion transmembrane transporter activity. Predicted to be involved in intracellular zinc ion homeostasis and zinc ion import into Golgi lumen. Located in endoplasmic reticulum. Orthologous to human SLC30A5 (solute carrier family 30 member 5). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See slc-30A5 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    9
    Sequence:
    Chromosome: I; NC_003279.8 (14358562..14367594)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Glutaredoxin domain-containing protein Neighboring gene Endoplasmic reticulum lectin 1 Neighboring gene pre-microRNA mir-8187 Neighboring gene Enoyl-CoA hydratase, mitochondrial Neighboring gene ncRNA Neighboring gene BBSome complex member BBS1

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables monoatomic cation transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables zinc ion transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables zinc ion transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in intracellular zinc ion homeostasis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in intracellular zinc ion homeostasis IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in monoatomic cation transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in zinc ion import into Golgi lumen IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in zinc ion transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in ER to Golgi transport vesicle membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in Golgi cisterna membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in cytoplasmic vesicle IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in endoplasmic reticulum HDA PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    Proton-coupled zinc antiporter SLC30A5
    NP_740931.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      14358562..14367594
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_170935.9NP_740931.2  Proton-coupled zinc antiporter SLC30A5 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_740931.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8WQB6
      Conserved Domains (1) summary
      COG1230
      Location:397696
      CzcD; Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism]