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    • Showing Current items.

    ndua-2 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 [ Caenorhabditis elegans ]

    Gene ID: 173279, updated on 9-Dec-2024

    Summary

    Official Symbol
    ndua-2
    Official Full Name
    NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2
    Primary source
    WormBase:WBGene00013406
    Locus tag
    CELE_Y63D3A.7
    See related
    AllianceGenome:WB:WBGene00013406
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in mitochondrial electron transport, NADH to ubiquinone. Predicted to be located in mitochondrial inner membrane. Predicted to be part of respiratory chain complex I. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 13. Orthologous to human NDUFA2 (NADH:ubiquinone oxidoreductase subunit A2). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See ndua-2 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    3
    Sequence:
    Chromosome: I; NC_003279.8 (14113636..14114085)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Protein tfg-1 Neighboring gene J domain-containing protein Neighboring gene TLC domain-containing protein fld-1 Neighboring gene histone acetyltransferase

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in mitochondrial electron transport, NADH to ubiquinone IC
    Inferred by Curator
    more info
     
    Component Evidence Code Pubs
    located_in mitochondrial inner membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
     
    part_of respiratory chain complex IEA
    Inferred from Electronic Annotation
    more info
     
    part_of respiratory chain complex I IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of respiratory chain complex I ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 

    General protein information

    Preferred Names
    NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2
    NP_493465.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      14113636..14114085
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_061064.8NP_493465.2  NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_493465.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9XWG2
      Conserved Domains (1) summary
      smart00916
      Location:2291
      L51_S25_CI-B8; Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain