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    trmt-6 tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 [ Caenorhabditis elegans ]

    Gene ID: 259389, updated on 9-Dec-2024

    Summary

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    Official Symbol
    trmt-6
    Official Full Name
    tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6
    Primary source
    WormBase:WBGene00014120
    Locus tag
    CELE_ZK858.7
    See related
    AllianceGenome:WB:WBGene00014120
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in tRNA methylation. Predicted to be part of tRNA (m1A) methyltransferase complex. Predicted to be active in nucleus. Orthologous to human TRMT6 (tRNA methyltransferase 6 non-catalytic subunit). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See trmt-6 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    7
    Sequence:
    Chromosome: I; NC_003279.8 (9141971..9144376, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene TM2 domain-containing protein ZK858.5 Neighboring gene Transmembrane 9 superfamily member Neighboring gene ncRNA Neighboring gene Amino acid transporter transmembrane domain-containing protein Neighboring gene ncRNA Neighboring gene Uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Generation of an external guide sequence library for a reverse genetic screen in Caenorhabditis elegans. Yan Q, et al. BMC Biotechnol, 2009 May 20. PMID 19457250, Free PMC Article
    2. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
    3. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
    4. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    5. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in tRNA methylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of tRNA (m1A) methyltransferase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of tRNA (m1A) methyltransferase complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6
    NP_492452.3
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      9141971..9144376 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_060051.4 → NP_492452.3  tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_492452.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q94416
      Conserved Domains (1) summary
      pfam04189
      Location:12 → 307
      Gcd10p; Gcd10p family
    Nucleotide Protein
    Heading Accession and Version

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