U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    vkmt-1 Protein-lysine methyltransferase vkmt-1 [ Caenorhabditis elegans ]

    Gene ID: 178175, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    vkmt-1
    Official Full Name
    Protein-lysine methyltransferase vkmt-1
    Primary source
    WormBase:WBGene00016591
    Locus tag
    CELE_C42C1.13
    See related
    AllianceGenome:WB:WBGene00016591
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable protein methyltransferase activity. Predicted to be involved in methylation. Orthologous to human VCPKMT (valosin containing protein lysine methyltransferase). [provided by Alliance of Genome Resources, Dec 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See vkmt-1 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    3
    Sequence:
    Chromosome: IV; NC_003282.8 (12278725..12279545)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Ovule protein Neighboring gene Vacuolar protein sorting-associated protein 8 central domain-containing protein;Vps8 domain-containing protein Neighboring gene Mannose-1-phosphate guanylyltransferase catalytic subunit beta Neighboring gene Aminopeptidase ltah-1.1 Neighboring gene PAP2_C domain-containing protein Neighboring gene MFS domain-containing protein;Major facilitator superfamily (MFS) profile domain-containing protein Neighboring gene Mitochondrial thiamine pyrophosphate carrier

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    2. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

    Go to the top of the page

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein methyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in methylation IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    Protein-lysine methyltransferase vkmt-1
    NP_001122759.1
    • Confirmed by transcript evidence
    NP_502334.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      12278725..12279545
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001129287.3 → NP_001122759.1  Protein-lysine methyltransferase vkmt-1 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001122759.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A3QMC4, A7IQW5
      Conserved Domains (1) summary
      cl17173
      Location:14 → 177
      AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...

    2. NM_069933.7 → NP_502334.2  Protein-lysine methyltransferase vkmt-1 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_502334.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A7IQW5
      Conserved Domains (1) summary
      cl17173
      Location:1 → 138
      AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A7IQW5.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous