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    F56C9.10 BCAS3 WD40 domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 176040, updated on 9-Dec-2024

    Summary

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    Official Symbol
    F56C9.10
    Official Full Name
    BCAS3 WD40 domain-containing protein
    Primary source
    WormBase:WBGene00018953
    Locus tag
    CELE_F56C9.10
    See related
    AllianceGenome:WB:WBGene00018953
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in response to starvation. Predicted to be active in cytoplasm. Is expressed in anal depressor muscle; body wall musculature; and nervous system. Human ortholog(s) of this gene implicated in Hengel-Maroofian-Schols syndrome. Orthologous to human BCAS3 (BCAS3 microtubule associated cell migration factor). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See F56C9.10 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    8
    Sequence:
    Chromosome: III; NC_003281.10 (7329705..7335316, complement)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Secreted protein Neighboring gene Long Arms of the Bivalent protein Neighboring gene Serine/threonine-protein phosphatase PP1-beta Neighboring gene ncRNA Neighboring gene Kinesin-associated protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. In Vivo Interaction Proteomics in Caenorhabditis elegans Embryos Provides New Insights into P Granule Dynamics. Chen JX, et al. Mol Cell Proteomics, 2016 May. PMID 26912668, Free PMC Article
    2. Depletion of endogenously biotinylated carboxylases enhances the sensitivity of TurboID-mediated proximity labeling in Caenorhabditis elegans. Artan M, et al. J Biol Chem, 2022 Sep. PMID 35933017, Free PMC Article
    3. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    4. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in autophagy IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in response to starvation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    BCAS3 WD40 domain-containing protein
    NP_001360481.1
    • Confirmed by transcript evidence
    NP_001360482.1
    • Confirmed by transcript evidence
    NP_741222.1
    • Confirmed by transcript evidence
    NP_741223.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      7329705..7335316 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_171190.6 → NP_741222.1  BCAS3 WD40 domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_741222.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2KY88

    2. NM_001372620.3 → NP_001360482.1  BCAS3 WD40 domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A486WY26

    3. NM_001372619.3 → NP_001360481.1  BCAS3 WD40 domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A486WX46

    4. NM_171882.6 → NP_741223.1  BCAS3 WD40 domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_741223.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8MQ22
    Nucleotide Protein
    Heading Accession and Version

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