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    elf-1 ETS domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 175226, updated on 9-Dec-2024

    Summary

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    Official Symbol
    elf-1
    Official Full Name
    ETS domain-containing protein
    Primary source
    WormBase:WBGene00016029
    Locus tag
    CELE_C24A1.2
    See related
    AllianceGenome:WB:WBGene00016029
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in gonad development and regulation of cell division. Predicted to be active in nucleus. Is expressed in head neurons and pharynx. Orthologous to human ELF1 (E74 like ETS transcription factor 1); ELF2 (E74 like ETS transcription factor 2); and ELF4 (E74 like ETS transcription factor 4). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See elf-1 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    8
    Sequence:
    Chromosome: III; NC_003281.10 (689169..715822)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene G protein-coupled receptor kinase 2 Neighboring gene Uncharacterized protein Neighboring gene Uncharacterized protein Neighboring gene Protein kinase domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene VPSAGDMMVRF-amide Neighboring gene Protein pat-12 Neighboring gene SXP/RAL-2 family protein Ani s 5-like cation-binding domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Cyclin D regulation of a sexually dimorphic asymmetric cell division. Tilmann C, et al. Dev Cell, 2005 Oct. PMID 16198291, Free PMC Article
    2. Gene regulatory logic of dopamine neuron differentiation. Flames N, et al. Nature, 2009 Apr 16. PMID 19287374, Free PMC Article
    3. Extensive rewiring and complex evolutionary dynamics in a C. elegans multiparameter transcription factor network. Reece-Hoyes JS, et al. Mol Cell, 2013 Jul 11. PMID 23791784, Free PMC Article
    4. Transcriptional regulation. Okkema PG, et al. WormBook, 2005 Dec 23. PMID 18050428, Free PMC Article
    5. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cell differentiation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in gonad development IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of cell division IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ETS domain-containing protein
    NP_001021180.1
    • Confirmed by transcript evidence
    NP_001021181.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      689169..715822
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001026010.5 → NP_001021181.1  ETS domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001021181.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      G4RYC9, Q400M2
      Conserved Domains (1) summary
      smart00413
      Location:293 → 379
      ETS; erythroblast transformation specific domain

    2. NM_001026009.3 → NP_001021180.1  ETS domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001021180.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2KYY1
      Conserved Domains (1) summary
      smart00413
      Location:294 → 380
      ETS; erythroblast transformation specific domain
    Nucleotide Protein
    Heading Accession and Version

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