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    cec-1 Chromo domain-containing protein cec-1 [ Caenorhabditis elegans ]

    Gene ID: 176190, updated on 9-Dec-2024

    Summary

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    Official Symbol
    cec-1
    Official Full Name
    Chromo domain-containing protein cec-1
    Primary source
    WormBase:WBGene00000414
    Locus tag
    CELE_ZK1236.2
    See related
    AllianceGenome:WB:WBGene00000414
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable chromatin binding activity and methylated histone binding activity. Predicted to be involved in heterochromatin formation. Predicted to be located in pericentric heterochromatin. Is expressed in several structures, including germ line; head neurons; oocyte; pharynx; and somatic cell. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See cec-1 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    4
    Sequence:
    Chromosome: III; NC_003281.10 (8426333..8428583)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Sop-2-related protein 1 Neighboring gene ncRNA Neighboring gene Translation factor GUF1 homolog, mitochondrial Neighboring gene Uncharacterized protein Neighboring gene TPR_REGION domain-containing protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. cec-1, a soma-specific chromobox-containing gene in C. elegans. Agostoni E, et al. Dev Biol, 1996 Sep 15. PMID 8812132
    2. Multiple Histone Methyl-Lysine Readers Ensure Robust Development and Germline Immortality in Caenorhabditis elegans. Saltzman AL, et al. Genetics, 2018 Nov. PMID 30185429, Free PMC Article
    3. Cell-Specific mRNA Profiling of the Caenorhabditis elegans Somatic Gonadal Precursor Cells Identifies Suites of Sex-Biased and Gonad-Enriched Transcripts. Kroetz MB, et al. G3 (Bethesda), 2015 Oct 23. PMID 26497144, Free PMC Article
    4. A transcriptional cofactor regulatory network for the C. elegans intestine. Horowitz BB, et al. G3 (Bethesda), 2023 Jul 5. PMID 37119809, Free PMC Article
    5. Extensive rewiring and complex evolutionary dynamics in a C. elegans multiparameter transcription factor network. Reece-Hoyes JS, et al. Mol Cell, 2013 Jul 11. PMID 23791784, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables chromatin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables methylated histone binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in heterochromatin formation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in chromosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in intracellular organelle IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in pericentric heterochromatin IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Chromo domain-containing protein cec-1
    NP_498862.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      8426333..8428583
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_066461.6 → NP_498862.1  Chromo domain-containing protein cec-1 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_498862.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P34618
      Conserved Domains (1) summary
      smart00298
      Location:8 → 59
      CHROMO; Chromatin organization modifier domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P34618.1

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