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    nlp-1 Neuropeptide-like protein 1 [ Caenorhabditis elegans ]

    Gene ID: 180661, updated on 9-Dec-2024

    Summary

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    Official Symbol
    nlp-1
    Official Full Name
    Neuropeptide-like protein 1
    Primary source
    WormBase:WBGene00003739
    Locus tag
    CELE_C01C4.1
    See related
    AllianceGenome:WB:WBGene00003739
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Involved in cellular response to carbon dioxide; negative regulation of nematode pharyngeal pumping; and thigmotaxis. Is expressed in intestine; lateral ganglion; and neurons. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See nlp-1 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    4
    Sequence:
    Chromosome: X; NC_003284.9 (3727574..3728446)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene Protein kinase domain-containing protein;Putative serine/threonine-protein kinase C01C4.3 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Uncharacterized protein Neighboring gene t-SNARE protein aex-4 Neighboring gene Uncharacterized protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Dissecting the signaling mechanisms underlying recognition and preference of food odors. Harris G, et al. J Neurosci, 2014 Jul 9. PMID 25009271, Free PMC Article
    2. Neuropeptide feedback modifies odor-evoked dynamics in Caenorhabditis elegans olfactory neurons. Chalasani SH, et al. Nat Neurosci, 2010 May. PMID 20364145, Free PMC Article
    3. The actions of Caenorhabditis elegans neuropeptide-like peptides (NLPs) on body wall muscle of Ascaris suum and pharyngeal muscle of C. elegans. Papaioannou S, et al. Acta Biol Hung, 2008. PMID 18652392
    4. HLH-14 is a C. elegans achaete-scute protein that promotes neurogenesis through asymmetric cell division. Frank CA, et al. Development, 2003 Dec. PMID 14627726
    5. NPY/NPF-Related Neuropeptide FLP-34 Signals from Serotonergic Neurons to Modulate Aversive Olfactory Learning in Caenorhabditis elegans. Fadda M, et al. J Neurosci, 2020 Jul 29. PMID 32576621, Free PMC Article

    See all (20) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in cellular response to carbon dioxide IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in negative regulation of nematode pharyngeal pumping IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in thigmotaxis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Neuropeptide-like protein 1
    NP_508640.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      3727574..3728446
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_076239.6 → NP_508640.1  Neuropeptide-like protein 1 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_508640.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q11088
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q11088.2

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