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    C24A3.4 Alpha-methylacyl-CoA racemase [ Caenorhabditis elegans ]

    Gene ID: 181140, updated on 2-Nov-2024

    Summary

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    Official Symbol
    C24A3.4
    Official Full Name
    Alpha-methylacyl-CoA racemase
    Primary source
    WormBase:WBGene00016034
    Locus tag
    CELE_C24A3.4
    See related
    AllianceGenome:WB:WBGene00016034
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable alpha-methylacyl-CoA racemase activity. Predicted to be involved in bile acid metabolic process. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in alpha-methylacyl-CoA racemase deficiency; congenital bile acid synthesis defect 4; and urinary bladder cancer. Orthologous to human AMACR (alpha-methylacyl-CoA racemase). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See C24A3.4 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    7
    Sequence:
    Chromosome: X; NC_003284.9 (8992406..8994763)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene TWiK family of potassium channels protein 18 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables alpha-methylacyl-CoA racemase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables catalytic activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in bile acid metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Alpha-methylacyl-CoA racemase
    NP_509517.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      8992406..8994763
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_077116.5 → NP_509517.2  Alpha-methylacyl-CoA racemase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_509517.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q18122
      Conserved Domains (1) summary
      cl19215
      Location:5 → 316
      CoA_transf_3; CoA-transferase family III
    Nucleotide Protein
    Heading Accession and Version

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