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    flp-7 TPMQRSSMVRF-amide 2 [ Caenorhabditis elegans ]

    Gene ID: 180854, updated on 2-Nov-2024

    Summary

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    Official Symbol
    flp-7
    Official Full Name
    TPMQRSSMVRF-amide 2
    Primary source
    WormBase:WBGene00001450
    Locus tag
    CELE_F49E10.3
    See related
    AllianceGenome:WB:WBGene00001450
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Enables neuropeptide receptor binding activity. Involved in negative regulation of locomotion and neuropeptide signaling pathway. Located in extracellular space. Is expressed in nerve ring and neurons. [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See flp-7 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    4
    Sequence:
    Chromosome: X; NC_003284.9 (5885865..5886833)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Mitochondria-eating protein C-terminal domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Exploring the neurotransmitter labyrinth in nematodes. Brownlee DJ, et al. Trends Neurosci, 1999 Jan. PMID 10088995
    2. Head-tail-head neural wiring underlies gut fat storage in Caenorhabditis elegans temperature acclimation. Motomura H, et al. Proc Natl Acad Sci U S A, 2022 Aug 9. PMID 35914124, Free PMC Article
    3. Characterization of an RFamide-related peptide orphan GPCR in C. elegans. Mertens I, et al. Ann N Y Acad Sci, 2005 Apr. PMID 15891075
    4. Evolution and Comparative Physiology of Luqin-Type Neuropeptide Signaling. Yañez-Guerra LA, et al. Front Neurosci, 2020. PMID 32132900, Free PMC Article
    5. A tachykinin-like neuroendocrine signalling axis couples central serotonin action and nutrient sensing with peripheral lipid metabolism. Palamiuc L, et al. Nat Commun, 2017 Jan 27. PMID 28128367, Free PMC Article

    See all (26) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables neuropeptide receptor binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of locomotion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in neuropeptide signaling pathway IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in neuropeptide signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in neuropeptide signaling pathway ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in extracellular space IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    TPMQRSSMVRF-amide 2
    NP_508985.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      5885865..5886833
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_076584.6 → NP_508985.1  TPMQRSSMVRF-amide 2 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_508985.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      G5EEC2
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    G5EEC2.1

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