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    abhd-14 AB hydrolase-1 domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 176923, updated on 2-Nov-2024

    Summary

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    Official Symbol
    abhd-14
    Official Full Name
    AB hydrolase-1 domain-containing protein
    Primary source
    WormBase:WBGene00021927
    Locus tag
    CELE_Y55F3AM.10
    See related
    AllianceGenome:WB:WBGene00021927
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable hydrolase activity. Predicted to be active in cytoplasm. Orthologous to several human genes including ABHD14B (abhydrolase domain containing 14B). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See abhd-14 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    5
    Sequence:
    Chromosome: IV; NC_003282.8 (1027787..1030039, complement)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Methyltransferase FkbM domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. In vivo CRISPR screening for phenotypic targets of the mir-35-42 family in C. elegans. Yang B, et al. Genes Dev, 2020 Sep 1. PMID 32820039, Free PMC Article
    2. Screening for cold tolerance genes in C. elegans, whose expressions are affected by anticancer drugs camptothecin and leptomycin B. Okahata M, et al. Sci Rep, 2024 Mar 5. PMID 38443452, Free PMC Article
    3. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
    4. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    5. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    AB hydrolase-1 domain-containing protein
    NP_500027.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      1027787..1030039 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_067626.6 → NP_500027.1  AB hydrolase-1 domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_500027.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9N366
      Conserved Domains (1) summary
      COG0596
      Location:72 → 241
      MhpC; Pimeloyl-ACP methyl ester carboxylesterase [Coenzyme transport and metabolism, General function prediction only]
    Nucleotide Protein
    Heading Accession and Version

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