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    R08D7.4 Complex 1 LYR protein domain-containing protein;Complex1_LYR_dom domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 176269, updated on 9-Dec-2024

    Summary

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    Official Symbol
    R08D7.4
    Official Full Name
    Complex 1 LYR protein domain-containing protein;Complex1_LYR_dom domain-containing protein
    Primary source
    WormBase:WBGene00011144
    Locus tag
    CELE_R08D7.4
    See related
    AllianceGenome:WB:WBGene00011144
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable protein-lysine N-methyltransferase activity. Predicted to be involved in regulation of translation. Predicted to be part of protein-containing complex. Orthologous to several human genes including EEF2KMT (eukaryotic elongation factor 2 lysine methyltransferase) and FAM86B2 (family with sequence similarity 86 member B2). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See R08D7.4 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    6
    Sequence:
    Chromosome: III; NC_003281.10 (8971892..8973671)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene BUD13 homolog Neighboring gene Putative RNA polymerase II subunit B1 CTD phosphatase rpap-2 Neighboring gene Eukaryotic translation initiation factor 3 subunit D Neighboring gene putative calcium-binding protein R08D7.5 Neighboring gene putative 3',5'-cyclic phosphodiesterase pde-2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables protein-lysine N-methyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of protein-containing complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Complex 1 LYR protein domain-containing protein;Complex1_LYR_dom domain-containing protein
    NP_001379047.1
    • Confirmed by transcript evidence
    NP_001379488.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      8971892..8973671
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      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001392169.1 → NP_001379047.1  Complex1_LYR_dom domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P30643
      Conserved Domains (1) summary
      cl17173
      Location:165 → 314
      AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...

    2. NM_001392168.1 → NP_001379488.1  Complex 1 LYR protein domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      B2MZB2
      Conserved Domains (1) summary
      cd20261
      Location:9 → 82
      Complex1_LYR_LYRM1; LYR (leucine-tyrosine-arginine) motif found in LYR motif-containing protein 1 (LYRM1) and similar proteins
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P30643.3

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