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    gcl-1 BTB domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 190457, updated on 9-Dec-2024

    Summary

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    Official Symbol
    gcl-1
    Official Full Name
    BTB domain-containing protein
    Primary source
    WormBase:WBGene00013382
    Locus tag
    CELE_Y62E10A.16
    See related
    AllianceGenome:WB:WBGene00013382
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Enables identical protein binding activity. Predicted to be involved in germ cell development. Orthologous to human GMCL1 (germ cell-less 1, spermatogenesis associated) and GMCL2 (germ cell-less 2, spermatogenesis associated). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See gcl-1 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    7
    Sequence:
    Chromosome: IV; NC_003282.8 (13408325..13412895, complement)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene MEiosis-to-MItosis transition associated Neighboring gene CYtochrome P450 family Neighboring gene Neuropeptide-Like Protein Neighboring gene Transcription factor aptf-2 Neighboring gene Pelle-like serine/threonine-protein kinase pik-1 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A combined binary interaction and phenotypic map of C. elegans cell polarity proteins. Koorman T, et al. Nat Cell Biol, 2016 Mar. PMID 26780296, Free PMC Article
    2. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article
    3. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
    4. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
    5. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables identical protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in germ cell development IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    BTB domain-containing protein
    NP_502585.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      13408325..13412895 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_070184.5 → NP_502585.1  BTB domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_502585.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9U1W5
      Conserved Domains (2) summary
      cd18305
      Location:55 → 169
      BTB_POZ_GCL; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Drosophila melanogaster protein germ cell-less (GCL) and similar proteins
      cl28903
      Location:170 → 248
      BACK; BACK (BTB and C-terminal Kelch) domain
    Nucleotide Protein
    Heading Accession and Version

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