bcc-1 SAM domain-containing protein [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: bcc-1
Official Full Name: SAM domain-containing protein
Primary source: WormBase:WBGene00000246
Locus tag: CELE_M7.3
See related: AllianceGenome:WB:WBGene00000246
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable RNA binding activity. Predicted to be active in cytoplasm. Is expressed in hypodermis. Human ortholog(s) of this gene implicated in diffuse cystic renal dysplasia. Orthologous to human BICC1 (BicC family RNA binding protein 1). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See bcc-1 in Genome Data Viewer

Location:: chromosome: IV

Exon count:: 15

Sequence:: Chromosome: IV; NC_003282.8 (11086074..11092552, complement)

Chromosome IV - NC_003282.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

M7.7 (e-PCR)
- UniSTS:307824

M7.3 (e-PCR)
- UniSTS:322254

M7.6 (e-PCR)
- UniSTS:322255

M7.4 (e-PCR)
- UniSTS:316912

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables RNA binding	IEA Inferred from Electronic Annotation more info
enables nucleic acid binding	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: SAM domain-containing protein

NP_502067.2

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003282.8 Reference assembly

Range

11086074..11092552 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_069666.6 → NP_502067.2 SAM domain-containing protein [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_502067.2

Status: REVIEWED

UniProtKB/TrEMBL

Q21593

Conserved Domains (2) summary

smart00454
Location:571 → 636

SAM; Sterile alpha motif

cd02394
Location:105 → 171

vigilin_like_KH; K homology RNA-binding domain_vigilin_like. The vigilin family is a large and extended family of multiple KH-domain proteins, including vigilin, also called high density lipoprotein binding protien (HBP), fungal Scp160 and bicaudal-C. Yeast Scp160p has ...