cogc-8 Conserved oligomeric Golgi complex subunit 8 [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: cogc-8
Official Full Name: Conserved oligomeric Golgi complex subunit 8
Primary source: WormBase:WBGene00019820
Locus tag: CELE_R02D3.2
See related: AllianceGenome:WB:WBGene00019820
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Involved in gonad morphogenesis and regulation of cell migration. Predicted to be located in Golgi membrane. Predicted to be part of Golgi transport complex. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type IIh. Orthologous to human COG8 (component of oligomeric golgi complex 8). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See cogc-8 in Genome Data Viewer

Location:: chromosome: IV

Exon count:: 9

Sequence:: Chromosome: IV; NC_003282.8 (240451..244130)

Chromosome IV - NC_003282.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

R02D3.2 (e-PCR)
- UniSTS:306367

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Process	Evidence Code	Pubs
involved_in gonad morphogenesis	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in intra-Golgi vesicle-mediated transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein transport	IEA Inferred from Electronic Annotation more info
involved_in regulation of cell migration	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in Golgi apparatus	IEA Inferred from Electronic Annotation more info
located_in Golgi membrane	IEA Inferred from Electronic Annotation more info
part_of Golgi transport complex	IBA Inferred from Biological aspect of Ancestor more info
part_of Golgi transport complex	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: Conserved oligomeric Golgi complex subunit 8

NP_499883.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003282.8 Reference assembly

Range

240451..244130

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_067482.4 → NP_499883.1 Conserved oligomeric Golgi complex subunit 8 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_499883.1

Status: REVIEWED

UniProtKB/Swiss-Prot

O44502

Conserved Domains (3) summary

pfam05887
Location:551 → 646

Trypan_PARP; Procyclic acidic repetitive protein (PARP)

pfam04124
Location:10 → 353

Dor1; Dor1-like family

cl14876
Location:323 → 387

Zinc_peptidase_like; Zinc peptidases M18, M20, M28, and M42