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    pals-37 Protein containing ALS2cr12 (ALS2CR12) signature [ Caenorhabditis elegans ]

    Gene ID: 13215782, updated on 2-Nov-2024

    Summary

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    Official Symbol
    pals-37
    Official Full Name
    Protein containing ALS2cr12 (ALS2CR12) signature
    Primary source
    WormBase:WBGene00138721
    Locus tag
    CELE_C54D10.14
    See related
    AllianceGenome:WB:WBGene00138721
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in positive regulation of cytokinesis. Predicted to be located in microtubule. Predicted to be active in centrosome and spindle pole. [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See pals-37 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    16
    Sequence:
    Chromosome: V; NC_003283.11 (12437440..12441520, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Serpentine Receptor, class H Neighboring gene pseudo Neighboring gene ncRNA Neighboring gene Protein containing ALS2cr12 (ALS2CR12) signature Neighboring gene Protein containing ALS2cr12 (ALS2CR12) signature

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Terminal uridylyltransferases target RNA viruses as part of the innate immune system. Le Pen J, et al. Nat Struct Mol Biol, 2018 Sep. PMID 30104661, Free PMC Article
    2. Multiple pals gene modules control a balance between immunity and development in Caenorhabditis elegans. Lažetić V, et al. PLoS Pathog, 2023 Jul. PMID 37463170, Free PMC Article
    3. The purine nucleoside phosphorylase pnp-1 regulates epithelial cell resistance to infection in C. elegans. Tecle E, et al. PLoS Pathog, 2021 Apr. PMID 33878133, Free PMC Article
    4. Screening for cold tolerance genes in C. elegans, whose expressions are affected by anticancer drugs camptothecin and leptomycin B. Okahata M, et al. Sci Rep, 2024 Mar 5. PMID 38443452, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in positive regulation of cytokinesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in positive regulation of cytokinesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in centrosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in centrosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in microtubule IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in spindle pole IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in spindle pole IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Protein containing ALS2cr12 (ALS2CR12) signature
    NP_001256416.1
    • Product from WormBase gene class pals;
      Confirmed by transcript evidence
    NP_001263871.1
    • Product from WormBase gene class pals;
      Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      12437440..12441520 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001269487.2 → NP_001256416.1  Protein containing ALS2cr12 (ALS2CR12) signature [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001256416.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      B6EU63
      Conserved Domains (1) summary
      PTZ00121
      Location:331 → 717
      PTZ00121; MAEBL; Provisional

    2. NM_001276942.3 → NP_001263871.1  Protein containing ALS2cr12 (ALS2CR12) signature [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001263871.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      J7SEY3
      Conserved Domains (1) summary
      PTZ00121
      Location:323 → 709
      PTZ00121; MAEBL; Provisional
    Nucleotide Protein
    Heading Accession and Version

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