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    thoc-7 THO complex subunit 7 homolog [ Caenorhabditis elegans ]

    Gene ID: 178353, updated on 2-Nov-2024

    Summary

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    Official Symbol
    thoc-7
    Official Full Name
    THO complex subunit 7 homolog
    Primary source
    WormBase:WBGene00007195
    Locus tag
    CELE_B0513.2
    See related
    AllianceGenome:WB:WBGene00007195
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in mRNA export from nucleus. Predicted to be located in nucleus. Predicted to be part of THO complex part of transcription export complex. Orthologous to human THOC7 (THO complex subunit 7). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See thoc-7 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    5
    Sequence:
    Chromosome: IV; NC_003282.8 (13882734..13884177)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Transposase Neighboring gene 60S ribosomal protein L29 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Caenorhabditis elegans THO complex is required for the mitotic cell cycle and development. Castellano-Pozo M, et al. PLoS One, 2012. PMID 23285047, Free PMC Article
    2. Depletion of endogenously biotinylated carboxylases enhances the sensitivity of TurboID-mediated proximity labeling in Caenorhabditis elegans. Artan M, et al. J Biol Chem, 2022 Sep. PMID 35933017, Free PMC Article
    3. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article
    4. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    5. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in mRNA export from nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of THO complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    part_of THO complex part of transcription export complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of THO complex part of transcription export complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    THO complex subunit 7 homolog
    NP_001255765.1
    • Confirmed by transcript evidence
    NP_001255766.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      13882734..13884177
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001268836.4 → NP_001255765.1  THO complex subunit 7 homolog [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001255765.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9U3S3
      Conserved Domains (1) summary
      pfam05615
      Location:3 → 131
      THOC7; Tho complex subunit 7

    2. NM_001268837.3 → NP_001255766.1  THO complex subunit 7 homolog [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001255766.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      D3YT70
    Nucleotide Protein
    Heading Accession and Version

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