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    cld-9 CUB-like domain-containing protein;CUB_2 domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 179869, updated on 9-Dec-2024

    Summary

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    Official Symbol
    cld-9
    Official Full Name
    CUB-like domain-containing protein;CUB_2 domain-containing protein
    Primary source
    WormBase:WBGene00009432
    Locus tag
    CELE_F35E12.8
    See related
    AllianceGenome:WB:WBGene00009432
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Involved in innate immune response. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See cld-9 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    7
    Sequence:
    Chromosome: V; NC_003283.11 (13749181..13751891, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene CUB-like domain-containing protein;CUB_2 domain-containing protein Neighboring gene CUB-like domain-containing protein Neighboring gene DeHydrogenases, Short chain Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Systemic and cell intrinsic roles of Gqalpha signaling in the regulation of innate immunity, oxidative stress, and longevity in Caenorhabditis elegans. Kawli T, et al. Proc Natl Acad Sci U S A, 2010 Aug 3. PMID 20647387, Free PMC Article
    2. Identifying evolutionarily conserved genes in the dietary restriction response using bioinformatics and subsequent testing in Caenorhabditis elegans. Ludewig AH, et al. Genes Nutr, 2014 Jan. PMID 24311442, Free PMC Article
    3. p38 MAPK regulates expression of immune response genes and contributes to longevity in C. elegans. Troemel ER, et al. PLoS Genet, 2006 Nov 10. PMID 17096597, Free PMC Article
    4. Transcriptome analyses describe the consequences of persistent HIF-1 over-activation in Caenorhabditis elegans. Feng D, et al. PLoS One, 2024. PMID 38517909, Free PMC Article
    5. A conserved role for a GATA transcription factor in regulating epithelial innate immune responses. Shapira M, et al. Proc Natl Acad Sci U S A, 2006 Sep 19. PMID 16968778, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in innate immune response HEP PubMed 
    involved_in innate immune response IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    CUB-like domain-containing protein;CUB_2 domain-containing protein
    NP_001256543.1
    • Confirmed by transcript evidence
    NP_001256544.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      13749181..13751891 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001269614.2 → NP_001256543.1  CUB-like domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001256543.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5EFQ6
      Conserved Domains (1) summary
      cl00049
      Location:17 → 131
      CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.

    2. NM_001269615.3 → NP_001256544.1  CUB_2 domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001256544.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      E0AHD6
    Nucleotide Protein
    Heading Accession and Version

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