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    grl-2 Ground-like domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 179777, updated on 9-Dec-2024

    Summary

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    Official Symbol
    grl-2
    Official Full Name
    Ground-like domain-containing protein
    Primary source
    WormBase:WBGene00001711
    Locus tag
    CELE_T16G1.8
    See related
    AllianceGenome:WB:WBGene00001711
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Is expressed in head and nervous system. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See grl-2 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    6
    Sequence:
    Chromosome: V; NC_003283.11 (12945075..12946858)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene CHK kinase-like domain-containing protein Neighboring gene CHK kinase-like domain-containing protein Neighboring gene ncRNA Neighboring gene EIF3k Neighboring gene Uncharacterized protein Neighboring gene Uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Caenorhabditis elegans Hedgehog-related proteins are tissue- and substructure-specific components of the cuticle and precuticle. Serra ND, et al. Genetics, 2024 Aug 7. PMID 38739761,
    2. Caenorhabditis elegans has scores of hedgehog-related genes: sequence and expression analysis. Aspöck G, et al. Genome Res, 1999 Oct. PMID 10523520
    3. Comprehensive analysis of gene expression patterns of hedgehog-related genes. Hao L, et al. BMC Genomics, 2006 Oct 31. PMID 17076889, Free PMC Article
    4. Evolution of hedgehog and hedgehog-related genes, their origin from Hog proteins in ancestral eukaryotes and discovery of a novel Hint motif. Bürglin TR. BMC Genomics, 2008 Mar 11. PMID 18334026, Free PMC Article
    5. Meta-Analysis of Caenorhabditis elegans Transcriptomics Implicates Hedgehog-Like Signaling in Host-Microbe Interactions. Zárate-Potes A, et al. Front Microbiol, 2022. PMID 35620104, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    General protein information

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    Preferred Names
    Ground-like domain-containing protein
    NP_506238.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      12945075..12946858
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_073837.5 → NP_506238.1  Ground-like domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_506238.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9XUP5
      Conserved Domains (2) summary
      pfam04155
      Location:293 → 364
      Ground-like; Ground-like domain
      pfam15488
      Location:83 → 151
      DUF4645; Domain of unknown function (DUF4645)
    Nucleotide Protein
    Heading Accession and Version

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