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    ugtp-1 UDP-galactose translocator 1 [ Caenorhabditis elegans ]

    Gene ID: 176227, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ugtp-1
    Official Full Name
    UDP-galactose translocator 1
    Primary source
    WormBase:WBGene00022721
    Locus tag
    CELE_ZK370.7
    See related
    AllianceGenome:WB:WBGene00022721
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable CMP-N-acetylneuraminate transmembrane transporter activity. Predicted to be involved in CMP-N-acetylneuraminate transmembrane transport. Located in Golgi medial cisterna and cortical granule. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type IIf. Orthologous to human SLC35A1 (solute carrier family 35 member A1). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ugtp-1 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    6
    Sequence:
    Chromosome: III; NC_003281.10 (8746216..8748701, complement)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene putative [pyruvate dehydrogenase (acetyl-transferring)] kinase, mitochondrial Neighboring gene DUF19 domain-containing protein Neighboring gene Dwarfin sma-2;MH2 domain-containing protein Neighboring gene Mitochondrial import receptor subunit tomm-70 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The ArfGEF GBF-1 Is Required for ER Structure, Secretion and Endocytic Transport in C. elegans. Ackema KB, et al. PLoS One, 2013. PMID 23840591, Free PMC Article
    2. Conserved role for Ataxin-2 in mediating endoplasmic reticulum dynamics. Del Castillo U, et al. Traffic, 2019 Jun. PMID 30989774, Free PMC Article
    3. Cortical granule exocytosis in C. elegans is regulated by cell cycle components including separase. Bembenek JN, et al. Development, 2007 Nov. PMID 17913784, Free PMC Article
    4. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
    5. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables CMP-N-acetylneuraminate transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables pyrimidine nucleotide-sugar transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in CMP-N-acetylneuraminate transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in pyrimidine nucleotide-sugar transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in Golgi medial cisterna IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in Golgi membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cortical granule IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    UDP-galactose translocator 1
    NP_498930.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      8746216..8748701 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_066529.8 → NP_498930.1  UDP-galactose translocator 1 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_498930.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P34632, Q02334
      Conserved Domains (2) summary
      TIGR00803
      Location:122 → 350
      nst; UDP-galactose transporter
      pfam04142
      Location:37 → 351
      Nuc_sug_transp; Nucleotide-sugar transporter
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q02334.2

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