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    somi-1 Zinc finger protein somi-1 [ Caenorhabditis elegans ]

    Gene ID: 179819, updated on 2-Nov-2024

    Summary

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    Official Symbol
    somi-1
    Official Full Name
    Zinc finger protein somi-1
    Primary source
    WormBase:WBGene00010868
    Locus tag
    CELE_M04G12.4
    See related
    AllianceGenome:WB:WBGene00010868
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable DNA binding activity and metal ion binding activity. Predicted to be involved in cell differentiation. Located in nucleus. Is expressed in several structures, including gonad; hypodermal cell; intestine; neurons; and vulval precursor cell. [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See somi-1 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    5
    Sequence:
    Chromosome: V; NC_003283.11 (13386058..13391395, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene 7TM GPCR serpentine receptor class x (Srx) domain-containing protein Neighboring gene IRF-2BP1_2 domain-containing protein;Interferon regulatory factor 2-binding protein 1 & 2 zinc finger domain-containing protein;RING-type domain-containing protein Neighboring gene cathepsin X Neighboring gene Soluble guanylate cyclase gcy-34 Neighboring gene ncRNA Neighboring gene ZP domain-containing protein Neighboring gene ncRNA Neighboring gene NADP-dependent oxidoreductase domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Caenorhabditis elegans SOMI-1 zinc finger protein and SWI/SNF promote regulation of development by the mir-84 microRNA. Hayes GD, et al. Genes Dev, 2011 Oct 1. PMID 21979920, Free PMC Article
    2. Caenorhabditis elegans SET1/COMPASS Maintains Germline Identity by Preventing Transcriptional Deregulation Across Generations. Robert VJ, et al. Front Cell Dev Biol, 2020. PMID 33072747, Free PMC Article
    3. Gene regulatory network inference in long-lived C. elegans reveals modular properties that are predictive of novel aging genes. Suriyalaksh M, et al. iScience, 2022 Jan 21. PMID 35036864, Free PMC Article
    4. Extensive rewiring and complex evolutionary dynamics in a C. elegans multiparameter transcription factor network. Reece-Hoyes JS, et al. Mol Cell, 2013 Jul 11. PMID 23791784, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. somi-1 coordinates a nuclear response that complements the activity of mir-84
      Title: The Caenorhabditis elegans SOMI-1 zinc finger protein and SWI/SNF promote regulation of development by the mir-84 microRNA.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Zinc finger protein somi-1
    NP_001360520.1
    • Confirmed by transcript evidence
    NP_001360558.1
    • Confirmed by transcript evidence
    NP_001379322.1
    • Confirmed by transcript evidence
    NP_506320.3
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      13386058..13391395 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_073919.6 → NP_506320.3  Zinc finger protein somi-1 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_506320.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5EBR5
      Conserved Domains (1) summary
      pfam13909
      Location:454 → 478
      zf-H2C2_5; C2H2-type zinc-finger domain

    2. NM_001373144.3 → NP_001360520.1  Zinc finger protein somi-1 [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A0A486WWJ9, A0A486WWS8, G5EBR5, Q8I4H1
      Conserved Domains (1) summary
      pfam13909
      Location:454 → 473
      zf-H2C2_5; C2H2-type zinc-finger domain

    3. NM_001392639.1 → NP_001379322.1  Zinc finger protein somi-1 [Caenorhabditis elegans]

      Status: REVIEWED

      Conserved Domains (1) summary
      pfam13909
      Location:425 → 444
      zf-H2C2_5; C2H2-type zinc-finger domain

    4. NM_001373145.2 → NP_001360558.1  Zinc finger protein somi-1 [Caenorhabditis elegans]

      Status: REVIEWED

      Conserved Domains (1) summary
      pfam13909
      Location:425 → 444
      zf-H2C2_5; C2H2-type zinc-finger domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A486WWJ9.1

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