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    M05D6.5 HIG1 domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 174357, updated on 9-Dec-2024

    Summary

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    Official Symbol
    M05D6.5
    Official Full Name
    HIG1 domain-containing protein
    Primary source
    WormBase:WBGene00010878
    Locus tag
    CELE_M05D6.5
    See related
    AllianceGenome:WB:WBGene00010878
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in mitochondrial respirasome assembly. Located in endoplasmic reticulum. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See M05D6.5 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    3
    Sequence:
    Chromosome: II; NC_003280.10 (8480487..8482203, complement)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Protein kinase domain-containing protein Neighboring gene Tyrosine-protein phosphatase domain-containing protein Neighboring gene Beta-lactamase-related domain-containing protein Neighboring gene TAil-Anchored Protein Neighboring gene Trimethyllysine dioxygenase, mitochondrial Neighboring gene Receptor-type tyrosine-protein phosphatase kappa;Receptor-type tyrosine-protein phosphatase mu;Tyrosine-protein phosphatase domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Rcf1 and Rcf2, members of the hypoxia-induced gene 1 protein family, are critical components of the mitochondrial cytochrome bc1-cytochrome c oxidase supercomplex. Strogolova V, et al. Mol Cell Biol, 2012 Apr. PMID 22310663, Free PMC Article
    2. Determining the sub-cellular localization of proteins within Caenorhabditis elegans body wall muscle. Meissner B, et al. PLoS One, 2011. PMID 21611156, Free PMC Article
    3. A genome-wide study of PDZ-domain interactions in C. elegans reveals a high frequency of non-canonical binding. Lenfant N, et al. BMC Genomics, 2010 Nov 26. PMID 21110867, Free PMC Article
    4. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in mitochondrial respirasome assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in endoplasmic reticulum HDA PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    HIG1 domain-containing protein
    NP_001254151.1
    • Confirmed by transcript evidence
    NP_001367209.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      8480487..8482203 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001267222.4 → NP_001254151.1  HIG1 domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001254151.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q21524
      Conserved Domains (1) summary
      pfam04588
      Location:78 → 128
      HIG_1_N; Hypoxia induced protein conserved region

    2. NM_001381527.1 → NP_001367209.1  HIG1 domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      B7WN91
      Conserved Domains (1) summary
      pfam04588
      Location:71 → 120
      HIG_1_N; Hypoxia induced protein conserved region
    Nucleotide Protein
    Heading Accession and Version

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