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    lron-9 eLRR (extracellular Leucine-Rich Repeat) ONly [ Caenorhabditis elegans ]

    Gene ID: 172529, updated on 9-Dec-2024

    Summary

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    Official Symbol
    lron-9
    Official Full Name
    eLRR (extracellular Leucine-Rich Repeat) ONly
    Primary source
    WormBase:WBGene00011971
    Locus tag
    CELE_T23G11.6
    See related
    AllianceGenome:WB:WBGene00011971
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in cell development. Predicted to be located in membrane. Is expressed in head neurons; muscle cell; seam cell; and ventral cord neurons. Orthologous to human LRG1 (leucine rich alpha-2-glycoprotein 1). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See lron-9 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    13
    Sequence:
    Chromosome: I; NC_003279.8 (7685066..7689403, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Golgin-84 Neighboring gene HAUS6_N domain-containing protein;Vacuolar protein sorting-associated protein VTA1 homolog Neighboring gene Rho-GAP domain-containing protein Neighboring gene Hepatocellular carcinoma-associated antigen 59 Neighboring gene Female germline-specific tumor suppressor gld-1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. IGLR-2, a Leucine-Rich Repeat Domain Containing Protein, Is Required for the Host Defense in Caenorhabditis elegans. Kuo CJ, et al. Front Immunol, 2020. PMID 33329523, Free PMC Article
    2. C. elegans BLMP-1 controls apical epidermal cell morphology by repressing expression of mannosyltransferase bus-8 and molting signal mlt-8. Wu YZ, et al. Dev Biol, 2022 Jun. PMID 35367457
    3. Large-scale RNAi screens identify novel genes that interact with the C. elegans retinoblastoma pathway as well as splicing-related components with synMuv B activity. Ceron J, et al. BMC Dev Biol, 2007 Apr 6. PMID 17417969, Free PMC Article
    4. Amino acid and protein specificity of protein fatty acylation in C. elegans. Zhang B, et al. Proc Natl Acad Sci U S A, 2024 Jan 30. PMID 38252833, Free PMC Article
    5. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in cell development IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    eLRR (extracellular Leucine-Rich Repeat) ONly
    NP_001021638.1
    • Product from WormBase gene class lron;
      Partially confirmed by transcript evidence
    NP_001076615.1
    • Product from WormBase gene class lron;
      Confirmed by transcript evidence
    NP_001122522.1
    • Product from WormBase gene class lron;
      Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      7685066..7689403 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001083146.7 → NP_001076615.1  eLRR (extracellular Leucine-Rich Repeat) ONly [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001076615.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O02329
      Conserved Domains (3) summary
      cd00116
      Location:234 → 456
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00033
      Location:160 → 183
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:280 → 340
      LRR_8; Leucine rich repeat

    2. NM_001129050.4 → NP_001122522.1  eLRR (extracellular Leucine-Rich Repeat) ONly [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001122522.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A5JYW0

    3. NM_001026467.6 → NP_001021638.1  eLRR (extracellular Leucine-Rich Repeat) ONly [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001021638.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q58A95
      Conserved Domains (3) summary
      cd00116
      Location:234 → 456
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00033
      Location:160 → 183
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:280 → 340
      LRR_8; Leucine rich repeat

    RNA

    1. NR_050271.1 RNA Sequence

      Status: REVIEWED

    Nucleotide Protein
    Heading Accession and Version

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