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    nhr-50 Nuclear receptor domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 180067, updated on 9-Dec-2024

    Summary

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    Official Symbol
    nhr-50
    Official Full Name
    Nuclear receptor domain-containing protein
    Primary source
    WormBase:WBGene00003640
    Locus tag
    CELE_C06C6.5
    See related
    AllianceGenome:WB:WBGene00003640
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in innate immune response. Predicted to be located in nucleus. Is expressed in intestine; nervous system; pharynx; rectal gland cell; and tail. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See nhr-50 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    7
    Sequence:
    Chromosome: V; NC_003283.11 (15997726..16000631, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene protein of unknown function WSN domain-containing protein Neighboring gene Uncharacterized protein Neighboring gene Uncharacterized protein Neighboring gene Nuclear Hormone Receptor family Neighboring gene ncRNA Neighboring gene pseudo

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Expression and function of members of a divergent nuclear receptor family in Caenorhabditis elegans. Miyabayashi T, et al. Dev Biol, 1999 Nov 15. PMID 10545240
    2. The molecular signature and cis-regulatory architecture of a C. elegans gustatory neuron. Etchberger JF, et al. Genes Dev, 2007 Jul 1. PMID 17606643, Free PMC Article
    3. Transcriptional regulation. Okkema PG, et al. WormBook, 2005 Dec 23. PMID 18050428, Free PMC Article
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in innate immune response IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Nuclear receptor domain-containing protein
    NP_507015.3
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      15997726..16000631 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_074614.8 → NP_507015.3  Nuclear receptor domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_507015.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      O62031
      Conserved Domains (2) summary
      smart00399
      Location:3 → 68
      ZnF_C4; c4 zinc finger in nuclear hormone receptors
      smart00430
      Location:156 → 327
      HOLI; Ligand binding domain of hormone receptors

    RNA

    1. NR_136353.1 RNA Sequence

      Status: REVIEWED

    2. NR_136354.1 RNA Sequence

      Status: REVIEWED

    3. NR_136352.1 RNA Sequence

      Status: REVIEWED

    Nucleotide Protein
    Heading Accession and Version

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