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    rps-26 Small ribosomal subunit protein eS26 [ Caenorhabditis elegans ]

    Gene ID: 173342, updated on 9-Dec-2024

    Summary

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    Official Symbol
    rps-26
    Official Full Name
    Small ribosomal subunit protein eS26
    Primary source
    WormBase:WBGene00004495
    Locus tag
    CELE_F39B2.6
    See related
    AllianceGenome:WB:WBGene00004495
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable mRNA binding activity. Predicted to be a structural constituent of ribosome. Involved in determination of adult lifespan. Predicted to be located in cytoplasmic side of rough endoplasmic reticulum membrane and ribosome. Predicted to be part of cytosolic small ribosomal subunit. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 10. Orthologous to several human genes including RPS26 (ribosomal protein S26). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See rps-26 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    2
    Sequence:
    Chromosome: I; NC_003279.8 (14759930..14760626)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene DNaJ domain (prokaryotic heat shock protein) Neighboring gene Transmembrane protein 107 Neighboring gene ncRNA Neighboring gene G-protein coupled receptors family 3 profile domain-containing protein Neighboring gene ncRNA Neighboring gene TrmE-type G domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome-wide RNA interference screen identifies previously undescribed regulators of polyglutamine aggregation. Nollen EA, et al. Proc Natl Acad Sci U S A, 2004 Apr 27. PMID 15084750, Free PMC Article
    2. Lifespan extension by conditions that inhibit translation in Caenorhabditis elegans. Hansen M, et al. Aging Cell, 2007 Feb. PMID 17266679
    3. A Sterile 20 Family Kinase and Its Co-factor CCM-3 Regulate Contractile Ring Proteins on Germline Intercellular Bridges. Rehain-Bell K, et al. Curr Biol, 2017 Mar 20. PMID 28285996, Free PMC Article
    4. Nucleolar proteins suppress Caenorhabditis elegans innate immunity by inhibiting p53/CEP-1. Fuhrman LE, et al. PLoS Genet, 2009 Sep. PMID 19763173, Free PMC Article
    5. An extensive requirement for transcription factor IID-specific TAF-1 in Caenorhabditis elegans embryonic transcription. Walker AK, et al. J Biol Chem, 2004 Apr 9. PMID 14726532

    See all (19) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables mRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cytoplasmic translation ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in determination of adult lifespan IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoplasmic side of rough endoplasmic reticulum membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of cytosolic small ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of cytosolic small ribosomal subunit ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in ribosome ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in rough endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Small ribosomal subunit protein eS26
    NP_001370049.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      14759930..14760626
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001383766.2 → NP_001370049.1  Small ribosomal subunit protein eS26 [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O45499
      Conserved Domains (1) summary
      pfam01283
      Location:1 → 103
      Ribosomal_S26e; Ribosomal protein S26e
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O45499.1

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