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    F02E9.10 WD_REPEATS_REGION domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 172630, updated on 9-Dec-2024

    Summary

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    Official Symbol
    F02E9.10
    Official Full Name
    WD_REPEATS_REGION domain-containing protein
    Primary source
    WormBase:WBGene00008533
    Locus tag
    CELE_F02E9.10
    See related
    AllianceGenome:WB:WBGene00008533
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be part of Cdc73/Paf1 complex. Orthologous to human SKIC8 (SKI8 subunit of superkiller complex). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See F02E9.10 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    10
    Sequence:
    Chromosome: I; NC_003279.8 (8427087..8429832, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Tartrate-resistant acid phosphatase type 5 Neighboring gene Paired amphipathic helix protein sin-3 Neighboring gene Oxidative stress-responsive serine-rich protein 1 Neighboring gene Dipeptidyl peptidase 3 Neighboring gene pseudo Neighboring gene Superoxide dismutase [Mn] 1, mitochondrial

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Component Evidence Code Pubs
    part_of Cdc73/Paf1 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    WD_REPEATS_REGION domain-containing protein
    NP_001021083.1
    • Confirmed by transcript evidence
    NP_001021084.1
    • Confirmed by transcript evidence
    NP_001122441.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      8427087..8429832 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001025912.6 → NP_001021083.1  WD_REPEATS_REGION domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001021083.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q95QM9
      Conserved Domains (2) summary
      sd00039
      Location:162 → 199
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:41 → 325
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    2. NM_001128969.5 → NP_001122441.1  WD_REPEATS_REGION domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001122441.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A5Z2V7
      Conserved Domains (2) summary
      sd00039
      Location:162 → 199
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:41 → 325
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    3. NM_001025913.5 → NP_001021084.1  WD_REPEATS_REGION domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001021084.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q564V0
      Conserved Domains (2) summary
      sd00039
      Location:98 → 135
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:98 → 261
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    Nucleotide Protein
    Heading Accession and Version

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