iff-2 Eukaryotic translation initiation factor 5A-2 [Caenorhabditis elegans] - Gene

Summary

Official Symbol: iff-2
Official Full Name: Eukaryotic translation initiation factor 5A-2
Primary source: WormBase:WBGene00002065
Locus tag: CELE_F54C9.1
See related: AllianceGenome:WB:WBGene00002065
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable translation elongation factor activity. Involved in several processes, including gonad morphogenesis; nematode larval development; and nematode male tail tip morphogenesis. Predicted to be located in cytoplasm. Is expressed in excretory cell; hypodermis; pharynx; rectal muscle; and spermatheca. Orthologous to human EIF5AL1 (eukaryotic translation initiation factor 5A like 1) and EIF5A2 (eukaryotic translation initiation factor 5A2). [provided by Alliance of Genome Resources, Dec 2024]
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Chromosome II - NC_003280.10 Genomic Context describing neighboring genes

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables RNA binding	IEA Inferred from Electronic Annotation more info
enables ribosome binding	IEA Inferred from Electronic Annotation more info
enables translation elongation factor activity	IBA Inferred from Biological aspect of Ancestor more info
enables translation elongation factor activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in gamete generation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in gonad morphogenesis	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in nematode larval development	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in nematode male tail tip morphogenesis	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of translational elongation	IEA Inferred from Electronic Annotation more info
involved_in positive regulation of translational termination	IEA Inferred from Electronic Annotation more info
involved_in translation	IEA Inferred from Electronic Annotation more info
involved_in translational elongation	IBA Inferred from Biological aspect of Ancestor more info
involved_in translational elongation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info

NP_001369877.1

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