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    try-1 Peptidase S1 domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 173856, updated on 9-Dec-2024

    Summary

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    Official Symbol
    try-1
    Official Full Name
    Peptidase S1 domain-containing protein
    Primary source
    WormBase:WBGene00006619
    Locus tag
    CELE_ZK546.15
    See related
    AllianceGenome:WB:WBGene00006619
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable serine-type endopeptidase activity. Predicted to be involved in proteolysis. Is expressed in germ line. Orthologous to human PRSS33 (serine protease 33). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See try-1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    5
    Sequence:
    Chromosome: II; NC_003280.10 (4948154..4949527, complement)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Ribosomal RNA-processing protein 14/surfeit locus protein 6 C-terminal domain-containing protein;SURF6 homolog gldi-11 Neighboring gene Leucine-rich repeat-containing protein 57 Neighboring gene Zygote defective protein 12 Neighboring gene Nudix hydrolase 3 Neighboring gene Proteasome subunit beta type-3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    2. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables serine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables serine-type peptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Peptidase S1 domain-containing protein
    NP_494910.2
    • Partially confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      4948154..4949527 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_062509.8 → NP_494910.2  Peptidase S1 domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_494910.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q23528
      Conserved Domains (1) summary
      cd00190
      Location:59 → 285
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    Nucleotide Protein
    Heading Accession and Version

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