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    F56A8.3 Leucine-rich repeat domain, L domain-like;Transmembrane protein [ Caenorhabditis elegans ]

    Gene ID: 176740, updated on 9-Dec-2024

    Summary

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    Official Symbol
    F56A8.3
    Official Full Name
    Leucine-rich repeat domain, L domain-like;Transmembrane protein
    Primary source
    WormBase:WBGene00010139
    Locus tag
    CELE_F56A8.3
    See related
    AllianceGenome:WB:WBGene00010139
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be located in membrane. Is expressed in intestine; neurons; pharynx; and rectal gland cell. Orthologous to human LRRC59 (leucine rich repeat containing 59). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See F56A8.3 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    9
    Sequence:
    Chromosome: III; NC_003281.10 (13256880..13262905)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Anoctamin Neighboring gene CAB39 protein Neighboring gene F-box domain-containing protein Neighboring gene F-box domain-containing protein Neighboring gene RRM domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    2. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
    3. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Leucine-rich repeat domain, L domain-like;Transmembrane protein
    NP_001366989.1
    • Confirmed by transcript evidence
    NP_499731.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      13256880..13262905
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001379979.2 → NP_001366989.1  Leucine-rich repeat domain, L domain-like [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q95ZS5
      Conserved Domains (3) summary
      PTZ00121
      Location:135 → 242
      PTZ00121; MAEBL; Provisional
      COG4886
      Location:7 → 128
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      sd00031
      Location:19 → 39
      LRR_1; leucine-rich repeat [structural motif]

    2. NM_067330.6 → NP_499731.1  Transmembrane protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_499731.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O45574
    Nucleotide Protein
    Heading Accession and Version

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