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    acdh-9 Acyl CoA DeHydrogenase [ Caenorhabditis elegans ]

    Gene ID: 173466, updated on 9-Dec-2024

    Summary

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    Official Symbol
    acdh-9
    Official Full Name
    Acyl CoA DeHydrogenase
    Primary source
    WormBase:WBGene00017874
    Locus tag
    CELE_F28A10.6
    See related
    AllianceGenome:WB:WBGene00017874
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable flavin adenine dinucleotide binding activity and oxidoreductase activity, acting on the CH-CH group of donors. Orthologous to human ACAD8 (acyl-CoA dehydrogenase family member 8). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See acdh-9 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    8
    Sequence:
    Chromosome: II; NC_003280.10 (846864..848603, complement)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene WSD domain-containing protein Neighboring gene Uncharacterized protein Neighboring gene 60S ribosomal protein L35 Neighboring gene Methyltransferase FkbM domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. CEST-2.2 overexpression alters lipid metabolism and extends longevity of mitochondrial mutants. Piazzesi A, et al. EMBO Rep, 2022 May 4. PMID 35297148, Free PMC Article
    2. Fatty acid desaturation and the regulation of adiposity in Caenorhabditis elegans. Brock TJ, et al. Genetics, 2007 Jun. PMID 17435249, Free PMC Article
    3. A Caenorhabditis elegans nutrient response system partially dependent on nuclear receptor NHR-49. Van Gilst MR, et al. Proc Natl Acad Sci U S A, 2005 Sep 20. PMID 16157872, Free PMC Article
    4. Comparative genomics and functional study of lipid metabolic genes in Caenorhabditis elegans. Zhang Y, et al. BMC Genomics, 2013 Mar 12. PMID 23496871, Free PMC Article
    5. The conserved histone chaperone LIN-53 is required for normal lifespan and maintenance of muscle integrity in Caenorhabditis elegans. Müthel S, et al. Aging Cell, 2019 Dec. PMID 31397537, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables flavin adenine dinucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity, acting on the CH-CH group of donors IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Acyl CoA DeHydrogenase
    NP_493832.1
    • Product from WormBase gene class acdh;
      Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      846864..848603 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_061431.4 → NP_493832.1  Acyl CoA DeHydrogenase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_493832.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q95YB2
      Conserved Domains (2) summary
      cd01162
      Location:27 → 403
      IBD; Isobutyryl-CoA dehydrogenase
      COG1960
      Location:26 → 401
      CaiA; Acyl-CoA dehydrogenase related to the alkylation response protein AidB [Lipid transport and metabolism]
    Nucleotide Protein
    Heading Accession and Version

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