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    F37A4.5 Uncharacterized protein [ Caenorhabditis elegans ]

    Gene ID: 185404, updated on 9-Dec-2024

    Summary

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    Official Symbol
    F37A4.5
    Official Full Name
    Uncharacterized protein
    Primary source
    WormBase:WBGene00018135
    Locus tag
    CELE_F37A4.5
    See related
    AllianceGenome:WB:WBGene00018135
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable metal-dependent deubiquitinase activity and proteasome binding activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process and protein deubiquitination. Predicted to be part of proteasome regulatory particle, lid subcomplex. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See F37A4.5 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    4
    Sequence:
    Chromosome: III; NC_003281.10 (6711890..6713191)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Rabphilin-1 Neighboring gene ncRNA Neighboring gene Chromatin-remodeling complex ATPase chain isw-1 Neighboring gene Uncharacterized protein Neighboring gene Ankyrin repeat-containing protein F37A4.4 Neighboring gene Uncharacterized protein Neighboring gene BTB and MATH domain-containing protein 41

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Large-scale RNAi screens identify novel genes that interact with the C. elegans retinoblastoma pathway as well as splicing-related components with synMuv B activity. Ceron J, et al. BMC Dev Biol, 2007 Apr 6. PMID 17417969, Free PMC Article
    2. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article
    3. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal-dependent deubiquitinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables metallopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables peptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables proteasome binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of proteasome regulatory particle, lid subcomplex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Uncharacterized protein
    NP_498470.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      6711890..6713191
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_066069.3 → NP_498470.1  Uncharacterized protein CELE_F37A4.5 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_498470.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P41883
      Conserved Domains (1) summary
      cd08069
      Location:22 → 296
      MPN_RPN11_CSN5; Mov34/MPN/PAD-1 family: proteasomal regulatory protein Rpn11 and signalosome complex subunit CSN5
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P41883.1

    Gene LinkOut

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