U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    cec-7 Chromo domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 176704, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    cec-7
    Official Full Name
    Chromo domain-containing protein
    Primary source
    WormBase:WBGene00012551
    Locus tag
    CELE_Y37D8A.11
    See related
    AllianceGenome:WB:WBGene00012551
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in chromatin organization and regulation of DNA-templated transcription. Predicted to be located in nucleus. Predicted to be part of NuA4 histone acetyltransferase complex. Orthologous to human MORF4L1 (mortality factor 4 like 1). [provided by Alliance of Genome Resources, Dec 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See cec-7 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    5
    Sequence:
    Chromosome: III; NC_003281.10 (12875783..12877577, complement)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Mortality factor related protein 1 Neighboring gene Signal peptidase complex subunit 2 Neighboring gene ENhancer of Uncoordination Neighboring gene Disintegrin and metalloproteinase domain-containing protein unc-71 Neighboring gene Uncharacterized protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Functional analysis of MRG-1: the ortholog of human MRG15 in Caenorhabditis elegans. Olgun A, et al. J Gerontol A Biol Sci Med Sci, 2005 May. PMID 15972600
    2. A transcriptional cofactor regulatory network for the C. elegans intestine. Horowitz BB, et al. G3 (Bethesda), 2023 Jul 5. PMID 37119809, Free PMC Article
    3. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article
    4. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in chromatin organization IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of NuA4 histone acetyltransferase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    Chromo domain-containing protein
    NP_001022827.1
    • Confirmed by transcript evidence
    NP_001022828.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      12875783..12877577 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001027656.7 → NP_001022827.1  Chromo domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001022827.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9XWW0
      Conserved Domains (2) summary
      smart00298
      Location:344 → 374
      CHROMO; Chromatin organization modifier domain
      pfam11717
      Location:427 → 476
      Tudor-knot; RNA binding activity-knot of a chromodomain

    2. NM_001027657.3 → NP_001022828.1  Chromo domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001022828.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q69Z09
      Conserved Domains (2) summary
      smart00298
      Location:251 → 281
      CHROMO; Chromatin organization modifier domain
      pfam11717
      Location:334 → 383
      Tudor-knot; RNA binding activity-knot of a chromodomain
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools