U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    ric-7 CRAL-TRIO domain-containing protein;DUF1336 domain-containing protein;Uncharacterized protein [ Caenorhabditis elegans ]

    Gene ID: 179894, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    ric-7
    Official Full Name
    CRAL-TRIO domain-containing protein;DUF1336 domain-containing protein;Uncharacterized protein
    Primary source
    WormBase:WBGene00010259
    Locus tag
    CELE_F58E10.1
    See related
    AllianceGenome:WB:WBGene00010259
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Involved in several processes, including positive regulation of protein localization to presynapse; positive regulation of synapse pruning; and secretion by cell. Located in mitochondrion and synapse. Is expressed in head muscle and neurons. [provided by Alliance of Genome Resources, Dec 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See ric-7 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    14
    Sequence:
    Chromosome: V; NC_003283.11 (13987164..14005912, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene GATA-type domain-containing protein Neighboring gene dietary restriction over expressed Neighboring gene RNA helicase Neighboring gene AN1-type domain-containing protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Polarized localization of kinesin-1 and RIC-7 drives axonal mitochondria anterograde transport. Wu Y, et al. J Cell Biol, 2024 May 6. PMID 38470363, Free PMC Article
    2. nu444 is a novel allele of pkc-1 in C. elegans. Wang H, et al. MicroPubl Biol, 2017 May 18. PMID 32550344, Free PMC Article
    3. RIC-7 promotes neuropeptide secretion. Hao Y, et al. PLoS Genet, 2012 Jan. PMID 22275875, Free PMC Article
    4. Axons degenerate in the absence of mitochondria in C. elegans. Rawson RL, et al. Curr Biol, 2014 Mar 31. PMID 24631238, Free PMC Article
    5. The Cell Death Pathway Regulates Synapse Elimination through Cleavage of Gelsolin in Caenorhabditis elegans Neurons. Meng L, et al. Cell Rep, 2015 Jun 23. PMID 26074078, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Polarized localization of kinesin-1 and RIC-7 drives axonal mitochondria anterograde transport.
      Title: Polarized localization of kinesin-1 and RIC-7 drives axonal mitochondria anterograde transport.
    Submit: New GeneRIF Correction

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in actin filament depolymerization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in dense core granule exocytosis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in mitochondrion localization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in peptide secretion, neurotransmission IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of defecation IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in positive regulation of defecation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of locomotion IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of protein localization to presynapse IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of synapse pruning IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of muscle contraction IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in regulation of muscle contraction IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of synapse organization IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in presynapse IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in synapse IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    CRAL-TRIO domain-containing protein;DUF1336 domain-containing protein;Uncharacterized protein
    NP_001041132.1
    • Confirmed by transcript evidence
    NP_001041133.1
    • Confirmed by transcript evidence
    NP_001294709.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      13987164..14005912 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001047667.5 → NP_001041132.1  DUF1336 domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001041132.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9XUW6

    2. NM_001047668.6 → NP_001041133.1  CRAL-TRIO domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001041133.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q1ZXS6

    3. NM_001307780.3 → NP_001294709.1  Uncharacterized protein CELE_F58E10.1 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001294709.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      N1NSI8
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools