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    gid-2 RING-Gid-type domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 180548, updated on 9-Dec-2024

    Summary

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    Official Symbol
    gid-2
    Official Full Name
    RING-Gid-type domain-containing protein
    Primary source
    WormBase:WBGene00020301
    Locus tag
    CELE_T07D1.2
    See related
    AllianceGenome:WB:WBGene00020301
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to contribute to ubiquitin-protein transferase activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be part of GID complex. Predicted to be active in cytoplasm and nucleus. Is expressed in E; Ea; and Ep. Orthologous to several human genes including RMND5A (required for meiotic nuclear division 5 homolog A). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See gid-2 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    6
    Sequence:
    Chromosome: X; NC_003284.9 (2429859..2438957, complement)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene GLutamate Receptor family (AMPA) Neighboring gene ncRNA Neighboring gene Soluble guanylate cyclase gcy-31;guanylate cyclase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Activin_recp domain-containing protein Neighboring gene Sex determination protein fox-1 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    2. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    contributes_to ubiquitin-protein transferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables ubiquitin-protein transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of GID complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    RING-Gid-type domain-containing protein
    NP_001382745.1
    • Confirmed by transcript evidence
    NP_001382746.1
    • Confirmed by transcript evidence
    NP_508444.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      2429859..2438957 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_076043.7 → NP_508444.1  RING-Gid-type domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_508444.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q22302
      Conserved Domains (2) summary
      COG5109
      Location:240 → 412
      COG5109; Uncharacterized conserved protein, contains RING Zn-finger [General function prediction only]
      cd16652
      Location:345 → 401
      dRing_Rmd5p_like; Degenerated RING (dRING) finger found in Saccharomyces cerevisiae required for meiotic nuclear division protein 5 (Rmd5p) and similar proteins

    2. NM_001395783.1 → NP_001382745.1  RING-Gid-type domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A8D9I9M5
      Conserved Domains (2) summary
      COG5109
      Location:224 → 396
      COG5109; Uncharacterized conserved protein, contains RING Zn-finger [General function prediction only]
      cd16652
      Location:329 → 385
      dRing_Rmd5p_like; Degenerated RING (dRING) finger found in Saccharomyces cerevisiae required for meiotic nuclear division protein 5 (Rmd5p) and similar proteins

    3. NM_001395784.1 → NP_001382746.1  RING-Gid-type domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A8D9MH66
      Conserved Domains (2) summary
      COG5109
      Location:27 → 145
      COG5109; Uncharacterized conserved protein, contains RING Zn-finger [General function prediction only]
      cd16652
      Location:78 → 134
      dRing_Rmd5p_like; Degenerated RING (dRING) finger found in Saccharomyces cerevisiae required for meiotic nuclear division protein 5 (Rmd5p) and similar proteins
    Nucleotide Protein
    Heading Accession and Version

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