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    R07G3.8 CYRIA/CYRIB Rac1 binding domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 174234, updated on 9-Dec-2024

    Summary

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    Official Symbol
    R07G3.8
    Official Full Name
    CYRIA/CYRIB Rac1 binding domain-containing protein
    Primary source
    WormBase:WBGene00019944
    Locus tag
    CELE_R07G3.8
    See related
    AllianceGenome:WB:WBGene00019944
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable small GTPase binding activity. Predicted to be involved in regulation of actin filament polymerization. Predicted to be located in membrane. Is expressed in nervous system and reproductive system. Orthologous to human CYRIA (CYFIP related Rac1 interactor A) and CYRIB (CYFIP related Rac1 interactor B). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See R07G3.8 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    6
    Sequence:
    Chromosome: II; NC_003280.10 (7618238..7620513, complement)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Uncharacterized protein Neighboring gene Immunoglobulin domain-containing protein oig-4 Neighboring gene ncRNA Neighboring gene Cell division control protein 42 homolog Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article
    2. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables small GTPase binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of actin filament polymerization IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    CYRIA/CYRIB Rac1 binding domain-containing protein
    NP_495599.1
    • Partially confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      7618238..7620513 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_063198.8 → NP_495599.1  CYRIA/CYRIB Rac1 binding domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_495599.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q09387
      Conserved Domains (1) summary
      pfam07159
      Location:32 → 328
      DUF1394; Protein of unknown function (DUF1394)
    Nucleotide Protein
    Heading Accession and Version

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