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    slc-36.4 Amino acid transporter transmembrane domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 186798, updated on 9-Dec-2024

    Summary

    Official Symbol
    slc-36.4
    Official Full Name
    Amino acid transporter transmembrane domain-containing protein
    Primary source
    WormBase:WBGene00010421
    Locus tag
    CELE_H32K16.1
    See related
    AllianceGenome:WB:WBGene00010421
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable L-amino acid transmembrane transporter activity. Predicted to be involved in L-amino acid transport and amino acid transmembrane transport. Predicted to be located in membrane. Predicted to be active in vacuolar membrane. Human ortholog(s) of this gene implicated in iminoglycinuria. Orthologous to several human genes including SLC36A1 (solute carrier family 36 member 1); SLC36A2 (solute carrier family 36 member 2); and SLC36A3 (solute carrier family 36 member 3). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See slc-36.4 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    10
    Sequence:
    Chromosome: I; NC_003279.8 (9149673..9153252)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Transmembrane 9 superfamily member Neighboring gene ncRNA Neighboring gene tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 Neighboring gene ncRNA Neighboring gene Uncharacterized protein Neighboring gene Protein-tyrosine phosphatase

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables L-amino acid transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables L-amino acid transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    involved_in L-alpha-amino acid transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in L-amino acid transport ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in amino acid transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in vacuolar membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    Amino acid transporter transmembrane domain-containing protein
    NP_492453.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      9149673..9153252
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_060052.3NP_492453.1  Amino acid transporter transmembrane domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_492453.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O62286
      Conserved Domains (1) summary
      pfam01490
      Location:62471
      Aa_trans; Transmembrane amino acid transporter protein