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    ceh-89 Homeodomain-only protein [ Caenorhabditis elegans ]

    Gene ID: 181523, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ceh-89
    Official Full Name
    Homeodomain-only protein
    Primary source
    WormBase:WBGene00009231
    Locus tag
    CELE_F28H6.2
    See related
    AllianceGenome:WB:WBGene00009231
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in neurons. Orthologous to human HOPX (HOP homeobox). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ceh-89 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    7
    Sequence:
    Chromosome: X; NC_003284.9 (14141946..14144889)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene tRNA-His Neighboring gene kynurenine--oxoglutarate transaminase Neighboring gene Serine/threonine-protein kinase akt-2 Neighboring gene Homeobox domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A molecular atlas of adult C. elegans motor neurons reveals ancient diversity delineated by conserved transcription factor codes. Smith JJ, et al. Cell Rep, 2024 Mar 26. PMID 38421866, Free PMC Article
    2. Unique homeobox codes delineate all the neuron classes of C. elegans. Reilly MB, et al. Nature, 2020 Aug. PMID 32814896, Free PMC Article
    3. Extensive rewiring and complex evolutionary dynamics in a C. elegans multiparameter transcription factor network. Reece-Hoyes JS, et al. Mol Cell, 2013 Jul 11. PMID 23791784, Free PMC Article
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Homeodomain-only protein
    NP_510356.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      14141946..14144889
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_077955.6 → NP_510356.2  Homeodomain-only protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_510356.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9XX95
      Conserved Domains (1) summary
      smart00389
      Location:92 → 137
      HOX; Homeodomain

    RNA

    1. NR_147806.1 RNA Sequence

      Status: REVIEWED

    Nucleotide Protein
    Heading Accession and Version

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