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    clec-82 C-type lectin domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 177064, updated on 9-Dec-2024

    Summary

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    Official Symbol
    clec-82
    Official Full Name
    C-type lectin domain-containing protein
    Primary source
    WormBase:WBGene00021873
    Locus tag
    CELE_Y54G2A.8
    See related
    AllianceGenome:WB:WBGene00021873
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Involved in defense response to Gram-positive bacterium. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See clec-82 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    10
    Sequence:
    Chromosome: IV; NC_003282.8 (2835664..2838723)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Up-regulated in Daf-2 domain-containing protein Neighboring gene Up-regulated in Daf-2 domain-containing protein Neighboring gene C-type lectin domain-containing protein Neighboring gene ncRNA Neighboring gene C-type lectin domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Hirudomacin: a Protein with Dual Effects of Direct Bacterial Inhibition and Regulation of Innate Immunity. Du Y, et al. Appl Environ Microbiol, 2023 Jul 26. PMID 37428035, Free PMC Article
    2. Defective apoptotic cell clearance activates innate immune response to protect Caenorhabditis elegans against pathogenic bacteria. Wan J, et al. Virulence, 2021 Dec. PMID 33372828, Free PMC Article
    3. Innate host defense requires TFEB-mediated transcription of cytoprotective and antimicrobial genes. Visvikis O, et al. Immunity, 2014 Jun 19. PMID 24882217, Free PMC Article
    4. Specificity of the innate immune system and diversity of C-type lectin domain (CTLD) proteins in the nematode Caenorhabditis elegans. Schulenburg H, et al. Immunobiology, 2008. PMID 18406370
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in defense response to Gram-positive bacterium IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    C-type lectin domain-containing protein
    NP_001023507.1
    • Confirmed by transcript evidence
    NP_001380093.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      2835664..2838723
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001028336.4 → NP_001023507.1  C-type lectin domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001023507.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2L0R0
      Conserved Domains (1) summary
      smart00034
      Location:22 → 145
      CLECT; C-type lectin (CTL) or carbohydrate-recognition domain (CRD)

    2. NM_001392272.1 → NP_001380093.1  C-type lectin domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q5W7E6
      Conserved Domains (1) summary
      smart00034
      Location:1 → 111
      CLECT; C-type lectin (CTL) or carbohydrate-recognition domain (CRD)
    Nucleotide Protein
    Heading Accession and Version

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