taf-2 Transcription initiation factor TFIID subunit 2 [Caenorhabditis elegans] - Gene

Summary

Official Symbol: taf-2
Official Full Name: Transcription initiation factor TFIID subunit 2
Primary source: WormBase:WBGene00006383
Locus tag: CELE_Y37E11B.4
See related: AllianceGenome:WB:WBGene00006383
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable chromatin binding activity and transcription cis-regulatory region binding activity. Predicted to contribute to RNA polymerase II general transcription initiation factor activity. Involved in embryo development and transcription initiation at RNA polymerase II promoter. Predicted to be located in nucleus. Predicted to be part of transcription factor TFIID complex. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 40. Orthologous to human TAF2 (TATA-box binding protein associated factor 2). [provided by Alliance of Genome Resources, Dec 2024]
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Chromosome IV - NC_003282.8 Genomic Context describing neighboring genes

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
contributes_to RNA polymerase II general transcription initiation factor activity	IBA Inferred from Biological aspect of Ancestor more info
enables chromatin binding	IBA Inferred from Biological aspect of Ancestor more info
enables metallopeptidase activity	IEA Inferred from Electronic Annotation more info
enables transcription cis-regulatory region binding	IBA Inferred from Biological aspect of Ancestor more info
enables zinc ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in embryo development ending in birth or egg hatching	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in transcription initiation at RNA polymerase II promoter	IBA Inferred from Biological aspect of Ancestor more info
involved_in transcription initiation at RNA polymerase II promoter	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info
part_of transcription factor TFIID complex	IBA Inferred from Biological aspect of Ancestor more info
part_of transcription factor TFIID complex	IEA Inferred from Electronic Annotation more info

NP_001343606.1

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