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    gldi-8 C2H2-type domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 176678, updated on 9-Dec-2024

    Summary

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    Official Symbol
    gldi-8
    Official Full Name
    C2H2-type domain-containing protein
    Primary source
    WormBase:WBGene00013734
    Locus tag
    CELE_Y111B2A.10
    See related
    AllianceGenome:WB:WBGene00013734
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See gldi-8 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    3
    Sequence:
    Chromosome: III; NC_003281.10 (12595994..12599729, complement)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene pseudo Neighboring gene CBS domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Enhancer of polycomb-like protein Neighboring gene ncRNA Neighboring gene WD_REPEATS_REGION domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. DEPS-1 is required for piRNA-dependent silencing and PIWI condensate organisation in Caenorhabditis elegans. Suen KM, et al. Nat Commun, 2020 Aug 25. PMID 32843637, Free PMC Article
    2. RNA targets and specificity of Staufen, a double-stranded RNA-binding protein in Caenorhabditis elegans. LeGendre JB, et al. J Biol Chem, 2013 Jan 25. PMID 23195953, Free PMC Article
    3. Extensive rewiring and complex evolutionary dynamics in a C. elegans multiparameter transcription factor network. Reece-Hoyes JS, et al. Mol Cell, 2013 Jul 11. PMID 23791784, Free PMC Article
    4. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    C2H2-type domain-containing protein
    NP_001379274.1
    • Confirmed by transcript evidence
    NP_499640.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      12595994..12599729 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001392218.1 → NP_001379274.1  C2H2-type domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9BHL3
      Conserved Domains (1) summary
      sd00017
      Location:194 → 215
      ZF_C2H2; C2H2 Zn finger [structural motif]

    2. NM_067239.4 → NP_499640.1  C2H2-type domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_499640.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9BHL4
      Conserved Domains (2) summary
      sd00017
      Location:312 → 333
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam15909
      Location:151 → 221
      zf-C2H2_8; C2H2-type zinc ribbon
    Nucleotide Protein
    Heading Accession and Version

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