U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    rpia-1 Probable-ribose 5-phosphate isomerase [ Caenorhabditis elegans ]

    Gene ID: 175995, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    rpia-1
    Official Full Name
    Probable-ribose 5-phosphate isomerase
    Primary source
    WormBase:WBGene00015101
    Locus tag
    CELE_B0280.3
    See related
    AllianceGenome:WB:WBGene00015101
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable ribose-5-phosphate isomerase activity. Predicted to be involved in D-ribose metabolic process and pentose-phosphate shunt, non-oxidative branch. Predicted to be active in cytoplasm. Is expressed in head neurons; intestine; nerve ring; pharynx; and tail neurons. Orthologous to human RPIA (ribose 5-phosphate isomerase A). [provided by Alliance of Genome Resources, Dec 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See rpia-1 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    4
    Sequence:
    Chromosome: III; NC_003281.10 (7123128..7124332)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Nuclear hormone receptor family member nhr-10 Neighboring gene U3 small nucleolar RNA-associated protein 18 homolog Neighboring gene Uncharacterized protein Neighboring gene WH1 domain-containing protein Neighboring gene Protection of telomeres homolog 1

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. D-ribose competitively reverses inhibition by D-psicose of larval growth in Caenorhabditis elegans. Sato M, et al. Biol Pharm Bull, 2009 May. PMID 19420771
    2. Dietary restriction by growth in axenic medium induces discrete changes in the transcriptional output of genes involved in energy metabolism in Caenorhabditis elegans. Castelein N, et al. Biotechnol J, 2008 Jun. PMID 18383023
    3. The RNA-binding protein repertoire of Arabidopsis thaliana. Marondedze C, et al. Sci Rep, 2016 Jul 11. PMID 27405932, Free PMC Article
    4. A modified TurboID approach identifies tissue-specific centriolar components in C. elegans. Holzer E, et al. PLoS Genet, 2022 Apr. PMID 35442950, Free PMC Article
    5. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

    Go to the top of the page

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables isomerase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ribose-5-phosphate isomerase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables ribose-5-phosphate isomerase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in D-ribose metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in pentose-phosphate shunt IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in pentose-phosphate shunt, non-oxidative branch IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in pentose-phosphate shunt, non-oxidative branch IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in small molecule metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    Probable-ribose 5-phosphate isomerase
    NP_498556.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      7123128..7124332
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_066155.8 → NP_498556.1  Probable-ribose 5-phosphate isomerase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_498556.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P41994
      Conserved Domains (1) summary
      TIGR00021
      Location:18 → 242
      rpiA; ribose 5-phosphate isomerase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P41994.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous