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    F35H10.10 G-protein coupled receptors family 3 profile domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 177627, updated on 9-Dec-2024

    Summary

    Official Symbol
    F35H10.10
    Official Full Name
    G-protein coupled receptors family 3 profile domain-containing protein
    Primary source
    WormBase:WBGene00018073
    Locus tag
    CELE_F35H10.10
    See related
    AllianceGenome:WB:WBGene00018073
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential; adenylate cyclase inhibiting G protein-coupled glutamate receptor activity; and neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration. Predicted to be involved in G protein-coupled glutamate receptor signaling pathway and regulation of glutamatergic synaptic transmission. Predicted to be located in membrane. Predicted to be active in postsynaptic density membrane. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See F35H10.10 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    12
    Sequence:
    Chromosome: IV; NC_003282.8 (8307315..8312946, complement)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Spindle and kinetochore-associated protein 2 Neighboring gene Centromere protein X Neighboring gene V-type proton ATPase 116 kDa subunit a 2 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

    Interactions

    General gene information

    Gene Ontology Provided by WormBase

    Component Evidence Code Pubs
    located_in membrane  
    is_active_in plasma membrane  
    is_active_in postsynaptic density membrane  

    General protein information

    Preferred Names
    G-protein coupled receptors family 3 profile domain-containing protein
    NP_501400.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      8307315..8312946 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_068999.8NP_501400.1  G-protein coupled receptors family 3 profile domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_501400.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5ECZ3
      Conserved Domains (2) summary
      cd13953
      Location:10721266
      7tm_classC_mGluR-like; metabotropic glutamate receptor-like class C family of seven-transmembrane G protein-coupled receptors superfamily
      cd06350
      Location:57354
      PBP1_GPCR_family_C-like; ligand-binding domain of membrane-bound glutamate receptors that mediate excitatory transmission on the cellular surface through initial binding of glutamate; categorized into ionotropic glutamate receptors (iGluRs) and metabotropic glutamate receptors (m
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