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    F56C11.3 Sulfhydryl oxidase [ Caenorhabditis elegans ]

    Gene ID: 171611, updated on 9-Dec-2024

    Summary

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    Official Symbol
    F56C11.3
    Official Full Name
    Sulfhydryl oxidase
    Primary source
    WormBase:WBGene00018955
    Locus tag
    CELE_F56C11.3
    See related
    AllianceGenome:WB:WBGene00018955
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable flavin adenine dinucleotide binding activity and flavin-dependent sulfhydryl oxidase activity. Predicted to be active in mitochondrion. Is expressed in body wall musculature; pharynx; and reproductive system. Human ortholog(s) of this gene implicated in kidney failure and renal fibrosis. Orthologous to human GFER (growth factor, augmenter of liver regeneration). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See F56C11.3 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    4
    Sequence:
    Chromosome: I; NC_003279.8 (182068..182772, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Carboxylic ester hydrolase Neighboring gene ncRNA Neighboring gene MARVEL domain-containing protein Neighboring gene tRNA Neighboring gene Serine/threonine-protein kinase ATM Neighboring gene Carbohydrate sulfotransferase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables flavin adenine dinucleotide binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables flavin-dependent sulfhydryl oxidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables flavin-dependent sulfhydryl oxidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables thiol oxidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Sulfhydryl oxidase
    NP_490690.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      182068..182772 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_058289.4 → NP_490690.1  Sulfhydryl oxidase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_490690.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O44975
      Conserved Domains (1) summary
      pfam04777
      Location:60 → 148
      Evr1_Alr; Erv1 / Alr family
    Nucleotide Protein
    Heading Accession and Version

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