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    xbx-4 DUF3719 domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 182822, updated on 9-Dec-2024

    Summary

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    Official Symbol
    xbx-4
    Official Full Name
    DUF3719 domain-containing protein
    Primary source
    WormBase:WBGene00016025
    Locus tag
    CELE_C23H5.3
    See related
    AllianceGenome:WB:WBGene00016025
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Is expressed in ciliated neurons; head neurons; and sensory neurons. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See xbx-4 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    3
    Sequence:
    Chromosome: IV; NC_003282.8 (2114637..2115829)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Cyclic nucleotide-binding domain-containing protein Neighboring gene BURP domain-containing protein;Reelin domain-containing protein;Uncharacterized protein Neighboring gene ncRNA Neighboring gene Globin domain-containing protein Neighboring gene Ground-like domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. xbx-4, a homolog of the Joubert syndrome gene FAM149B1, acts via the CCRK and RCK kinase cascade to regulate cilia morphology. Maurya AK, et al. Curr Biol, 2021 Dec 20. PMID 34731674, Free PMC Article
    2. Analysis of xbx genes in C. elegans. Efimenko E, et al. Development, 2005 Apr. PMID 15790967
    3. The C. elegans regulatory factor X (RFX) DAF-19M module: A shift from general ciliogenesis to cell-specific ciliary and behavioral specialization. Ahn S, et al. Cell Rep, 2022 Apr 12. PMID 35417689
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. xbx-4, a homolog of the Joubert syndrome gene FAM149B1, acts via the CCRK and RCK kinase cascade to regulate cilia morphology.
      Title: xbx-4, a homolog of the Joubert syndrome gene FAM149B1, acts via the CCRK and RCK kinase cascade to regulate cilia morphology.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Homology

    General protein information

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    Preferred Names
    DUF3719 domain-containing protein
    NP_500165.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      2114637..2115829
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_067764.5 → NP_500165.1  DUF3719 domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_500165.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O61830
      Conserved Domains (1) summary
      pfam12516
      Location:36 → 76
      DUF3719; Protein of unknown function (DUF3719)
    Nucleotide Protein
    Heading Accession and Version

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